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Do CellBrite dyes specifically stain the plasma membrane?

CellBrite cytoplasmic membrane stains are lipophilic carbocyanine dyes. These dyes undergo an increase in fluorescence when they insert into lipid bilayers. Lipophilic carbocyanine dyes stably label the plasma membrane and other intracellular membranes of cells. They also can be used to stain artificial lipid bilayers.

If cells are returned to culture after staining, membrane internalization will occur, resulting in more intracellular staining and less surface membrane staining over time.

Category: CellBrite™ Cytoplasmic Membrane Stains

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