Cellular Senescence Assay Kit

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Product Description

Cellular senescence is a state of permanent cell-cycle arrest induced by cell age, stress, or certain cytotoxic drugs. Senescent cells show enlarged, flattened morphology and upregulation of beta-galactosidase activity. This kit is designed for beta-galactosidase staining using the blue chromogenic substrate X-gal under buffer conditions that allow selective staining of senescence-associated beta-galactosidase activity (SA-β-gal). X-gal staining of SA-β-gal activity has been reported for fresh-frozen tissue cryosections, but is not compatible with formalin-fixed paraffin-embedded (FFPE) tissue samples.

The kit contains enough reagents for 100 assays in 35 mm dishes with 2 mL staining volume, the volume can be scaled as needed depending on the size of the specimen or culture dish.

Kit contents:

30031A: X-gal 2 x 100 mg
99803: 10X Fixative Solution 20 mL
99804: Cellular Senescence Staining Buffer 200 mL


Additional Information


200 assays

Flyer (PDF): Apoptosis, Necrosis, and Cell Viability Assays web

MSDS (PDF): MSDS 30031

Protocol (PDF): PI-30031

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

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Please note that products with recommended storage at 4°C or -20°C may ship at ambient temperature. This will not affect product performance. When you receive the product, place it under the recommended storage conditions.

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