CF™660R Annexin V conjugate is Annexin V labeled with our superior far-red fluorescent dye CF™660R. Annexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the cytoplasmic surface of the cell membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasma membrane, making itself available for Annexin V binding.
CF™660R is a bright and exceptionally photostable dye that absorbs at 663 nm and emits fluorescence at 682 nm in the borderline spectral region between far-red and near-IR. CF™660R is ideal for confocal microscopy, where it can add a long wavelength color in multi-color imaging.