CF™680 picolyl azide reacts with alkyne to form 1,2,3-triazole by 1,3-dipolar Huisgen cycloaddition through the use of a much lower copper (I) concentration without sacrificing reaction efficiency. CF™680 is brighter than other spectrally similar dyes. Most importantly, antibody conjugates prepared from CF™680 have by far the best signal-to-noise ratio than antibody conjugates prepared from other spectrally similar dyes. Please also check out our CF™680R, an extremely photostable rhodamine-based near-IR dye. Please download the CF™680 dye flyer for more details.