CF™680R Annexin V conjugate is Annexin V labeled with our superior far-red/near-infrared fluorescent dye CF™680R. Annexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the cytoplasmic surface of the cell membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasma membrane, making itself available for Annexin V binding. CF™680R Annexin V does not contain azide or other potentially toxic materials, and thus is suitable for in vivo imaging.
CF™680R has unrivaled photostability among spectrally similar dyes. Download the CF™680R flyer for more information.