Monoclonal anti CD38 (AT1)

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Product Description

CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).

Deaglio S et. al. J Immunol. 1998;160(1):395-402

Additional Information

Conjugation

Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP

Size

50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type

Primary

Host species

Mouse

Reactivity (target)

CD38 (AT1)

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone

AT1

Molecular weight

~45 kDa (Glycoprotein); 35 kDa (protein core)

Synonyms

Acute Lymphoblastic Leukemia Cells Antigen; ADP Ribosyl Cyclase 1; cADP-ribose Hydrolase 1; CD38H; NAD(+) Nucleosidase; NIM-R5 Antigen; p45; T10

Entrez gene ID

952

SwissProt

P28907

Unigene

479214

Immunogen

human T cell line CCRF-CEM

Species reactivity

Human

Applications

Flow cytometry, Immunofluorescence

Cellular localization

Cell surface, cytoplasm and nucleus

Application notes

Flow Cytometry (0.5-1 ug/million cells/0.1 mL), Immunofluorescence, Optimal dilution for a specific application should be determined by user

Positive control

CCRF-CEM cells, Tonsil, Spleen or Skin

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

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