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DNA Binding Dyes

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    Product

    Actinomycin D

    From: $149 Sizes: 10 mgCatalog #: 40038

    Actinomycin D is a nonfluorescent GC-selective intercalator. Similar to 7-AAD (cat. no. 40038), actinomycin D has also been used for chromosome banding studies.

     
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    DiSC2(5) (High Purity)

    From: $80 Sizes: 50 mgCatalog #: 40041

    DiSC2(5) (3,3′-Diethylthiadicarbocyanine, iodide) binds to DNA-DNA or PNA-DNA duplexes with a large blue-shift of the absorption spectrum. Binding of the dye to PNA-DNA hybrid, in particular, blue-shifts the dye absorption spectrum by as much as 115 nm, offering a visual method to detect nucleic acid hybridization (1,2).

     
    Product

    DODC (High Purity)

    From: $80 Sizes: 50 mgCatalog #: 40040

    DODC (DiOC2(5)) has been reported to bind to triplex DNA as well as dimeric hairpin quadruplex DNA (1). Binding of the dye to triplex DNA quenches the fluorescence of the dye and red-shifts the dye absorption peak.

     
    Product

    Ethidium Bromide, 10 mg/mL in H2O

    From: $76 Sizes: 10 mLCatalog #: 40042

    Ethidium bromide (EtBr) is a widely used nucleic acid gel stain although it is also a known potent mutagen. EtBr is an intercalating DNA-binding dye with little sequence preference.

     
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    Hoechst

    From: $197 Sizes: 10 mL (10 mg/mL), 100 mgCatalog #:
    40044
    , 40046, 40047, - 40045View allHide

    Hoechst dyes are cell membrane-permeant, minor groove-binding blue fluorescent DNA stains. Hoechst dyes are widely used in cell cycle and apoptosis studies as nuclear counterstains.

     
    Product

    PMAxx™ Dye, 20 mM in H2O

    From: $159 Sizes: 100 uLCatalog #: 40069

    Viability PCR dye, a new and improved version of the popular viability dye propidium monoazide (PMA).

     
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    Propidium Iodide (PI)

    From: $61 Sizes: 10 mL (1 mg/mL in Water), 2 mL (50 ug/mL in Buffer), 100 mgCatalog #:
    40016
    , 40017, - 40048View allHide

    A membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a mixed live-dead population and also used as a counterstain in multicolor fluorescent assays.

     
    Product

    PMA (Propidium Monoazide)

    From: $167 Sizes: 100 uL, 1 mgCatalog #:
    40013
    , - 40019View allHide

    A photo-reactive DNA-binding dye typically used in viability PCR (v-PCR) of microorganisms like bacteria, viruses, and fungi.

     
    Product

    Ethidium Monoazide Bromide (EMA)

    From: $210 Sizes: 5 mgCatalog #: 40015

    A photo-activated fluorescent nucleic acid binding dye used to selectively and covalently label dead cells in the presence of live cells for viability PCR, fluorescent microscopy, and flow cytometry.