Membrane Potential & Nerve Terminal Dyes

The styryl dye RH237 is a fast-responding potentiometric probe that is primarily used for functional imaging of neurons.

The styryl dye RH414 is a fast-responding potentiometric probe that is primarily used for functional imaging of neurons.

RH421 is a fast responding membrane potential dye, exhibiting >20% fluorescence change per 100 mV on neuroblastoma cells.

The styryl dye RH795 is a fast-responding potentiometric probe that is primarily used for functional imaging of neurons. The dye is spectrally similar to RH414 (61016), but exhibits different physiological effects during staining. For example, RH414 causes arterial constriction during cortex staining, while RH795 does not (see references 1,2).

SCAS (4-Sulfonato calix[8]arene, sodium salt) is a quencher developed by Biotium to reduce background fluorescence when using our fixable AM dyes, SynaptoGreen and SynaptoRed dyes. Unlike ADVASEP-7, SCAS dramatically lowers background fluorescence as soon as it is added to the preparation without the need for repeated wash steps.

SGC3 is a coumarin styryl dye that binds to membranes in a manner similar to the FM® dyes. It becomes highly fluorescent upon insertion into lipid bilayers.

SGC5 is a coumarin styryl dye that binds to membranes in a manner similar to the FM® dyes. It becomes highly fluorescent upon insertion into lipid bilayers.

TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.

TMRM (Tetramethylrhodamine methyl ester, perchlorate) and TMRE are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.