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Receptor/Ion Channel Toxins & Probes

Fluorescently-labeled toxins can be used to label or inhibit receptors or ion channels on neurons. Biotium offers these labeled with a variety of bright, stable CF® Dyes.  α-Bungarotoxin binds to the acetylcholine receptor. Cholera Toxin B binds to GM1 gangliosides in lipid rafts. Tetrodotoxin reversibly blocks excitable sodium channels.

Biotium also offers other fluorescently-labeled molecules to bind to cell surface receptors. Transferrin binds to its receptor and is internalized by endocytosis. cAMP can be used to probe cAMP receptors.

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    α-Bungarotoxin, CF® Dye and Other Conjugates

    Sizes: 100 ug, 10 x 50 ug, 500 ug, 0.5 mgCatalog #: 00026-100ug, 00002, 00003, 00004, 00005, 00006, 00007, 00009, 00011, 00012, 00013, 00014, 00015, 00016, 00018, 00026, 00003-100ug, 00004-100ug, 00005-100ug, 00006-100ug, 00007-100ug, 00009-100ug, 00018-100ug, - 00002-100ugView allHide

    Conjugates of α-Bungarotoxin labeled with a selection of our CF® dyes and other labels. Labeled α-bungarotoxin conjugates can be used for staining nicotinic acetylcholine receptors at neuromuscular junctions in tissue sections.

    Conjugation
    Don’t see what you’re looking for? Contact us for more conjugation options.
    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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    100 ug
    10 x 50 ug
    500 ug
    0.5 mg
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    Conjugates of α-Bungarotoxin labeled with a selection of our CF® dyes and other labels. Labeled α-bungarotoxin conjugates can be used for staining nicotinic acetylcholine receptors at neuromuscular junctions in tissue sections.

     

    CF® Dye cAMP

    Sizes: 100 ugCatalog #: 00036, - 00037View allHide

    Fluorescently labeled cAMP analogs that can be used to probe cAMP receptors.

    Conjugation
    Don’t see what you’re looking for? Contact us for more conjugation options.
    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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    100 ug
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    Fluorescently labeled cAMP analogs that can be used to probe cAMP receptors.

     

    Cholera Toxin Subunit B CF® Dye Conjugates

    Sizes: 100 ugCatalog #: 00070, 00071, 00072, 00073, 00074, 00075, 00076, 00077, 00078, - 00079View allHide

    Binds GM1 ganglioside in lipid rafts and is used as a retrograde neuronal tracer for live imaging or on fixed cells.

    Conjugation
    Don’t see what you’re looking for? Contact us for more conjugation options.
    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
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    100 ug
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    Binds GM1 ganglioside in lipid rafts and is used as a retrograde neuronal tracer for live imaging or on fixed cells.

     

    Transferrin (human) CF® Dye Conjugates

    Sizes: 1 mgCatalog #: 00081, 00082, 00083, 00084, 00085, 00086, - 00087View allHide

    Labeled human transferrin is used for microscopic studies of the endosomal pathway and/or transferrin uptake studies.

    Conjugation
    Don’t see what you’re looking for? Contact us for more conjugation options.
    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
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    1 mg
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    Labeled human transferrin is used for microscopic studies of the endosomal pathway and/or transferrin uptake studies.

     

    α-Bungarotoxin

    From: $150 Sizes: 1 mgCatalog #: 00010-1

    A high affinity inhibitor of the nicotinic acetylcholine receptor in the neuromuscular junction. Blocks acetylcholine activity at the postsynaptic membrane.

    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
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    Qty
    1 mg
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    A high affinity inhibitor of the nicotinic acetylcholine receptor in the neuromuscular junction. Blocks acetylcholine activity at the postsynaptic membrane.

     

    Biotin-cAMP

    From: $245 Sizes: 1 mg, 20 x 50 ugCatalog #: 00020, - 00020-1View allHide

    A biotin-conjugated cAMP analog that can be used to probe cAMP receptors.

    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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    1 mg
    20 x 50 ug
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    A biotin-conjugated cAMP analog that can be used to probe cAMP receptors.

     

    Biotin-cGMP, Diisopropylethylammonium Salt

    From: $273 Sizes: 1 mg, 20 x 50 ugCatalog #: 00021, - 00021-1View allHide

    A biotinylated cyclic nucleotide that is an important second messenger in many biological processes and has been used as a tracer in immunoassays.

    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
    Catalog #
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    Qty
    1 mg
    20 x 50 ug
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    A biotinylated cyclic nucleotide that is an important second messenger in many biological processes and has been used as a tracer in immunoassays.

     

    Biotin-XX-α-Bungarotoxin

    From: $355 Sizes: 0.5 mgCatalog #: 00017

    A high affinity inhibitor of the nicotinic acetylcholine receptor in the neuromuscular junction. Blocks acetylcholine activity at the postsynaptic membrane. The biotin conjugate can be subsequently labeled with anti-biotin antibodies, avidin, or streptavidin for signal amplification.

    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
    Catalog #
    price
    Qty
    0.5 mg
    Clear selection
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    ADD TO CART
    (Please select quantity above )

    A high affinity inhibitor of the nicotinic acetylcholine receptor in the neuromuscular junction. Blocks acetylcholine activity at the postsynaptic membrane. The biotin conjugate can be subsequently labeled with anti-biotin antibodies, avidin, or streptavidin for signal amplification.

     

    Cyanine 644-cAMP

    From: $409 Sizes: 1 mg, 20 x 50 ugCatalog #: 00022, - 00022-1View allHide

    A fluorescently labeled cAMP analog that can be used to probe cAMP receptors.

    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
    Catalog #
    price
    Qty
    1 mg
    20 x 50 ug
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    A fluorescently labeled cAMP analog that can be used to probe cAMP receptors.

     

    Tetrodotoxin

    From: $211 Sizes: 1 mgCatalog #: 00060, - 00061View allHide

    This toxin reversibly blocks the sodium channels of neurons and has been a widely used tool for mechanistic studies of neurons, skeletal muscle, and cardiac muscle cells.

    Format
    Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
    Size
    Catalog #
    price
    Qty
    1 mg
    Clear selection
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    ADD TO CART
    (Please select quantity above )

    This toxin reversibly blocks the sodium channels of neurons and has been a widely used tool for mechanistic studies of neurons, skeletal muscle, and cardiac muscle cells.