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Membrane Potential & Nerve Terminal Dyes

Biotium offers a wide selection of synaptic vesicle dyes, as well as fast-responding and slow-responding membrane potential dyes.

Learn more about Membrane Potential & Nerve Terminal Dyes. Also see our Probes for Neuroscience Research and Indicators for Calcium & Other Ions.

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    Product

    TMRM

    From: $240 Sizes: 25 mgCatalog #: 70017

    TMRM (Tetramethylrhodamine methyl ester, perchlorate) and TMRE are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.

     
    Product

    Dipicrylamine

    From: $238 Sizes: 25 mgCatalog #: 60037

    Dipicrylamine (DPA) is a nonfluorescent anionic membrane dye. With its absorbance in the blue region of the visible spectrum, DPA can be used as a FRET quencher for a variety of fluorescent donor dyes.

     
    Product

    DiOC6(3)

    From: $215 Sizes: 100 mgCatalog #: 70009

    DiOC6(3) (3,3′-Dihexyloxacarbocyanine,iodide) is a green fluorescent membrane dye that has been used to stain the ER in both live and fixed cells. The dye has also been used to study structural interactions and dynamics of the ER in neurons and yeast.

     
    Product

    AM4-66

    From: $342 Sizes: 1 mgCatalog #: 70050

    A fixable red fluorescent nerve terminal probe that is spectrally identical to SynaptoRed™ C2 (also called FM®4-64).

     
    Product

    HM1-43

    From: $353 Sizes: 1 mgCatalog #: 70053

    HM1-43 is a fixable, activity-dependent fluorescent nerve terminal probe.

     
    Product

    DiOC2(3)

    From: $225 Sizes: 100 mgCatalog #: 70008

    DiOC2(3) (3,3′-Diethyloxacarbocyanine, iodide) has been used for measuring membrane potentials in bacteria. The green fluorescent dye forms red fluorescent aggregates with increasing membrane potential.

     
    Product

    RH795

    From: $337 Sizes: 5 mgCatalog #: 61019

    The styryl dye RH795 is a fast-responding potentiometric probe that is primarily used for functional imaging of neurons. The dye is spectrally similar to RH414 (61016), but exhibits different physiological effects during staining. For example, RH414 causes arterial constriction during cortex staining, while RH795 does not (see references 1,2).

     
    Product

    DiOC5(3)

    From: $225 Sizes: 100 mgCatalog #: 70007

    DiOC5(3) and DiOC6(3) are two of the most widely used carbocyanine dyes used for membrane potential measurements.

     
    Product

    RH237

    From: $229 Sizes: 5 mgCatalog #: 61018

    The styryl dye RH237 is a fast-responding potentiometric probe that is primarily used for functional imaging of neurons.

     
    Product

    RH421

    From: $337 Sizes: 25 mgCatalog #: 61017

    RH421 is a fast responding membrane potential dye, exhibiting >20% fluorescence change per 100 mV on neuroblastoma cells.

     
    Product

    SGC5

    From: $259 Sizes: 1 mgCatalog #: 70057

    SGC5 is a coumarin styryl dye that binds to membranes in a manner similar to the FM® dyes. It becomes highly fluorescent upon insertion into lipid bilayers.

     
    Product

    SGC3

    From: $259 Sizes: 1 mgCatalog #: 70056

    SGC3 is a coumarin styryl dye that binds to membranes in a manner similar to the FM® dyes. It becomes highly fluorescent upon insertion into lipid bilayers.

     
    Product

    AM3-25

    From: $389 Sizes: 1 mgCatalog #: 70051

    AM3-25 is a lipophilic styryl dye that has an amine group at the hydrophilic head. The amine group reacts with formaldehyde or glutaldehyde to make the dye fixable.

     
    Product

    SynaptoGreen™ C5 (Equivalent to FM®1-84)

    From: $311 Sizes: 5 mg, 5 x 1 mgCatalog #:
    70046
    , - 70047View allHide

    SynaptoGreen™ C5 is similar to SynaptoGreen™ C4 (70020), except that the lipophilic tail is one carbon longer.

     
    Product

    SynaptoGreen™ C18 (Equivalent to FM®3-25)

    From: $479 Sizes: 5 mg, 5 x 1 mgCatalog #:
    70048
    , - 70049View allHide

    SynaptoGreen™ C18 (equivalent to FM®3-25) is a membrane stain with a chemical structure similar to other nerve terminal dyes, except that it has the longest lipophilic tail (C18). Because of its large size, it is used as a control for ion channel permeability of nerve terminal dyes.

     
    Product

    SynaptoGreen™ C1

    From: $311 Sizes: 5 mg, 5 x 1 mgCatalog #:
    70042
    , - 70043View allHide

    SynaptoGreen™ C1 has the shortest (one-carbon) lipophilic tail and is the most water soluble of the nerve terminal dye series. Thus it is expected to have the slowest on-rate and the fastest off-rate among the SynaptoGreen™ dyes.