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The Full Spectrum

A Biotium Blog

Background Reducers for Improved Fluorescent Stains
Background Reducers for Improved Fluorescent Stains
October 9, 2020
Like a bright sky obscuring the stars, background fluorescence in microscopy makes specific ...
Like a bright sky obscuring the stars, background fluorescence in microscopy makes specific signals harder to see—only the brightest points shine through. Reducing background improves ...
Christopher Pratt, PhDChristopher Pratt, PhD
Getting the Whole Picture with Spectral Flow Cytometry
Getting the Whole Picture with Spectral Flow Cytometry
August 26, 2020
Why Use Flow Cytometry? Flow cytometry is capable of distinguishing individual cells based on size, shape, and expression levels of dozens of ...
Christopher Pratt, PhDChristopher Pratt, PhD
Blowing Up the Microscopic with Expansion Microscopy
Blowing Up the Microscopic with Expansion Microscopy
July 29, 2020
Greetings from the Biotium blog team! In this post we would like to present one of our guest writers, Dr. Christopher Pratt, who will talk about ...
Christopher Pratt, PhDChristopher Pratt, PhD
Pushing Biology Forward with Super Resolution
Pushing Biology Forward with Super Resolution
July 8, 2020
Super resolution microscopy has revolutionized our understanding of biology by shedding light on the molecular world beyond the diffraction ...
Christopher Pratt, PhDChristopher Pratt, PhD
Luminescence: Mechanisms and Applications for 4 Prominent Techniques
Luminescence: Mechanisms and Applications for 4 Prominent Techniques
June 8, 2020
Luminescence – or the emission of light from a substance that has not been physically heated – is commonly used in science to provide ...
Nisha Cooch, PhDNisha Cooch, PhD
An Overview of Fluorescence Microscopy
An Overview of Fluorescence Microscopy
May 6, 2020
In the 1670s, Dutch scientist Antonie Von Leeuwenhoek first discovered microbial life forms through his simple light microscope, a finding that ...
Gopal Ramakrishnan, PhDGopal Ramakrishnan, PhD
CF® Dyes. What started it all? Part 2. The Chemistry of Fluorescence
CF® Dyes. What started it all? Part 2. The Chemistry of Fluorescence
March 3, 2020
Fei Mao, PhD. CEO, CSO and Co-Founder of Biotium Welcome back! In Part 1 of this blog series we briefly explored the history of fluorescent dyes. ...
Eric Torres, PhDEric Torres, PhD
What Does Vaping Vitamin E Acetate Do To Your Lungs?
What Does Vaping Vitamin E Acetate Do To Your Lungs?
January 15, 2020
Concerns over the impacts of vaping on public health have been steadily growing over the last decade. However, it wasn’t until August 2019 when ...
Eric Torres, PhDEric Torres, PhD
CF® Dyes. What started it all? Part 1. A History of Fluorescence
CF® Dyes. What started it all? Part 1. A History of Fluorescence
November 22, 2019
Here at Biotium, we pride ourselves in delivering innovative fluorescent solutions that fuel scientific breakthroughs. From immunofluorescence to ...
Eric Torres, PhDEric Torres, PhD
Your Go-To Guide for Protein Stains
Your Go-To Guide for Protein Stains
September 10, 2019
From pink to blue to near-IR, protein stains come in a wide variety of colors. As protein biologists, these stains play a crucial role in our ...
Eric Torres, PhDEric Torres, PhD
Microbe Puzzle
Microbe Puzzle
June 18, 2019
Take a break and test your microbiology knowledge with our Microbe Acrostic puzzle! Instructions: An acrostic is similar to a crossword puzzle, ...
Lori Roberts, PhDLori Roberts, PhD
Happy anniversary, NucView®! A decade of real-time apoptosis detection
Happy anniversary, NucView®! A decade of real-time apoptosis detection
November 19, 2018
img.attachment-post-thumbnail.size-post-thumbnail.wp-post-image {display: none;} NucView® technology: A decade of real-time apoptosis detection ...
Alexis Madrid, PhDAlexis Madrid, PhD
The Application of Toxins and Poisons in Cell and Molecular Biology
The Application of Toxins and Poisons in Cell and Molecular Biology
October 31, 2018
In nature, countless species have evolved to produce compounds that give them a distinct evolutionary advantage. Often, they come in the form of ...
Jeff Jung, Scientist IJeff Jung, Scientist I
The Chemist Tool Kit
The Chemist Tool Kit
September 17, 2018
Key Lab Instruments Used in Making Your Fluorescent Dyes Bustling pumps, beeping monitors, and flashing red and green lights; you might feel like ...
Jeff Jung, Scientist IJeff Jung, Scientist I
Making Colors In The Chem Lab
Making Colors In The Chem Lab
July 18, 2018
Working in the chemistry R&D lab at Biotium is…. How should I put this? A very COLORFUL job! When you specialize in designing fluorescent ...
Patrick McGarraugh, PhDPatrick McGarraugh, PhD
12 years later: Viability PCR using PMA and PMAxx™ dyes
12 years later: Viability PCR using PMA and PMAxx™ dyes
June 1, 2018
Biotium developed PMA dye for viability PCR 12 years ago, an advance that has spawned countless publications and contributed to basic research, ...
Alexis Madrid, PhDAlexis Madrid, PhD
Nothing left to fear about labeling your antibody with PE, APC, and PerCP
Nothing left to fear about labeling your antibody with PE, APC, and PerCP
May 17, 2018
Label your antibody with PE, APC, and PerCP like a pro (but without all those columns) The phycobiliproteins R-PE (commonly referred to simply as ...
Lori Roberts, PhDLori Roberts, PhD
Safe and Eco-friendly Gel Stains (Happy Earth Day!)
Safe and Eco-friendly Gel Stains (Happy Earth Day!)
May 2, 2018
Green tips on Gel Safety – Switch-over to the only proven ‘safe’ gel stains! Spring clean – Go Green: April 22nd was ...
Saloni Pasta, PhDSaloni Pasta, PhD
On the lookout for artifacts from DAPI and Hoechst in fluorescence microscopy
On the lookout for artifacts from DAPI and Hoechst in fluorescence microscopy
March 21, 2018
Photoconversion of DAPI and Hoechst Usually the first step of fluorescence imaging of cells is to focus on DAPI- or Hoechst-stained nuclei ...
Lori Roberts, PhDLori Roberts, PhD
Switching from agar plates to v-PCR for bacteria viability testing – What you need to know
Switching from agar plates to v-PCR for bacteria viability testing – What you need to know
March 2, 2018
Switching from culturing to v-PCR for bacteria viability testing The problem with plating Counting the number of living bacteria in a sample is a ...
Alexis Madrid, PhDAlexis Madrid, PhD