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The Full Spectrum

A Biotium Blog

Bring Out Your Dead: Viability PCR to Exclude Dead Cells in Microbial Population and Diversity Studies
Bring Out Your Dead: Viability PCR to Exclude Dead Cells in Microbial Population and Diversity Studies
Have you tried v-PCR yet? In this blog post we explore the endless applications for v-PCR in ...
Have you tried v-PCR yet? In this blog post we explore the endless applications for v-PCR in microbiology, sanitation, and clinical research.
Cell Viability- Where to Begin?
Cell Viability- Where to Begin?
Exploring the many tools and metrics for assessing cell viability, including assays for cytotoxicity, cellular activity, and apoptosis.
Bringing Light to Extracellular Vesicles
Bringing Light to Extracellular Vesicles
A deep dive into exosomes, their origins, methods for analysis, and tremendous potential for medicine and research.
An Interview with STORM expert Ke Xu on Super-Resolution Microscopy
An Interview with STORM expert Ke Xu on Super-Resolution Microscopy
Dr. Ke Xu, Ph.D, a leading STORM scientist at UC Berkeley, discusses the challenges and prospects of super-resolution microscopy.
Seeing More and Brighter Colors with Tyramide Signal Amplification
Seeing More and Brighter Colors with Tyramide Signal Amplification
Let's discuss tyramide signal amplification (TSA), a powerful tool for spatial proteomics and producing bright and high-resolution images.
Easy and Fun Science Experiments to Try with Kids at Home
Easy and Fun Science Experiments to Try with Kids at Home
Peak your child's scientific curiosity with these fun and easy ideas to explore DNA, proteins, and fluorescence. Hands-on science for grade K-12.
Background Reducers for Improved Fluorescent Stains
Background Reducers for Improved Fluorescent Stains
Issues with high immunofluorescence background? Check out the best tools to reduce background and improve image quality.
Getting the Whole Picture with Spectral Flow Cytometry
Getting the Whole Picture with Spectral Flow Cytometry
A brief overview of the exciting technology behind spectral cytometry, and how it's advancing the field of flow cytometry.
Blowing Up the Microscopic with Expansion Microscopy
Blowing Up the Microscopic with Expansion Microscopy
Biological structures too small to image? Blow it up instead! Chris Pratt, PhD explores a fascinating imaging technique known as expansion microscopy.
Pushing Biology Forward with Super Resolution
Pushing Biology Forward with Super Resolution
Our resident blog writer Christopher Pratt, PhD explores super-resolution microscopy and the creative tricks used to see beyond the diffraction limit.
Luminescence: Mechanisms and Applications for 4 Prominent Techniques
Luminescence: Mechanisms and Applications for 4 Prominent Techniques
An overview of luminescent techniques used in biological research including: bioluminescence, fluorescence, phosphorescence, and chemiluminescence.
An Overview of Fluorescence Microscopy
An Overview of Fluorescence Microscopy
Learn more about how fluorescence microscopes work as well as specialized variants that have advanced modern biological research.
CF® Dyes. What started it all? Part 2. The Chemistry of Fluorescence
CF® Dyes. What started it all? Part 2. The Chemistry of Fluorescence
In the final entry of our 2-part blog series, we’ll look at how CF® dyes are the next evolutionary step in fluorescent probes.
What Does Vaping Vitamin E Acetate Do To Your Lungs?
What Does Vaping Vitamin E Acetate Do To Your Lungs?
Lets explore the science behind vitamin E acetate as a vaping additive and the potential link to the EVALI outbreak.
CF® Dyes. What started it all? Part 1. A History of Fluorescence
CF® Dyes. What started it all? Part 1. A History of Fluorescence
Where did FITC, rhodamine, and Alexa Fluor® dyes come from? Find out in part 1 of this 2-part blog series on the history of fluorescent dyes.
Your Go-To Guide for Protein Stains
Your Go-To Guide for Protein Stains
Wondering if you should use CBB or silver stain for that gel? Find out with this comprehensive guide on protein stains!
Microbe Puzzle
Microbe Puzzle
Bored waiting for your cells to grow? Kill time and test your knowledge with this Microbe Acrostic puzzle!
Happy anniversary, NucView®! A decade of real-time apoptosis detection
Happy anniversary, NucView®! A decade of real-time apoptosis detection
A look back at NucView®, the apoptosis tool scientists were waiting for.
The Application of Toxins and Poisons in Cell and Molecular Biology
The Application of Toxins and Poisons in Cell and Molecular Biology
Natural substances that are very bad for eating, but great for research!
The Chemist Tool Kit
The Chemist Tool Kit
Let's explore the key lab instruments used to make fluorescent dyes.
Making Colors In The Chem Lab
Making Colors In The Chem Lab
Curious about what it's like to make fluorescent dyes in the lab? Our expert dye chemist Patrick McGarraugh provides some colorful insight.
12 years later: Viability PCR using PMA and PMAxx™ dyes
12 years later: Viability PCR using PMA and PMAxx™ dyes
Let's take a look back on the many uses of viability PCR in basic research, diagnostics and food safety over the years.
Nothing left to fear about labeling your antibody with PE, APC, and PerCP
Nothing left to fear about labeling your antibody with PE, APC, and PerCP
Never waste antibody with these optimized kits for labeling phycobiliproteins.
Safe and Eco-friendly Gel Stains (Happy Earth Day!)
Safe and Eco-friendly Gel Stains (Happy Earth Day!)
Check out these non-toxic and non-hazardous alternatives to ethidium bromide and other mutagenic DNA gel stains.
On the lookout for artifacts from DAPI and Hoechst in fluorescence microscopy
On the lookout for artifacts from DAPI and Hoechst in fluorescence microscopy
Photoconversion and cross-talk from blue nuclear dyes can ruin your image. Check out these tips on how to avoid it.
Switching from agar plates to v-PCR for bacteria viability testing – What you need to know
Switching from agar plates to v-PCR for bacteria viability testing – What you need to know
Important considerations to help you obtain the best possible data for your next v-PCR experiment.