Dyes for Mitochondria & Other Organelles
Biotium sells a range of dyes to stain organelles such as the mitochondria and lysosomes in cells. Many of the mitochondria dyes are dependent on mitochondrial membrane potential and can therefore be used to monitor membrane potential changes that occur during processes such as apoptosis.
MitoView™ Dyes stain the mitochondria in living cells. They come in 3 colors, including both membrane potential-dependent and -independent options.
We also offer a wide selection of classical potential-dependent mitochondrial dyes such as JC-1, TMRE, TMRM.
LysoView™ Dyes stain the lysosomes in living cells. Available in 5 colors, plus a novel UV-inducible version.
LipidSpot™ stains lipid droplets, cytoplasmic organelles involved in the storage and regulation of triglycerides and cholesterol esters.
Showing 1–16 of 21 results
LipidSpot™ Lipid Droplet Stains
LipidSpot™ Dyes rapidly stains lipid droplets in live cells or fixed cells, with no wash step required. Available with green or red/far-red fluorescence.
LipidSpot™ Dyes rapidly stains lipid droplets in live cells or fixed cells, with no wash step required. Available with green or red/far-red fluorescence.
MitoView™ Dyes
MitoView™ dyes are fluorogenic mitochondrial stains for live cells. The dyes rapidly accumulate in mitochondria and can be imaged without washing. They are available with blue, green, far-red, and near-infrared fluorescence.
MitoView™ dyes are fluorogenic mitochondrial stains for live cells. The dyes rapidly accumulate in mitochondria and can be imaged without washing. They are available with blue, green, far-red, and near-infrared fluorescence.
Light-on LysoView™ 555
Light-On LysoView™ 555 is a red fluorogenic lysosome dye with pH-dependent fluorescence. Light-On LysoView™ dye is unique among commercially available lysosomotropic dyes in that its fluorescence in cells is activated by exposure to UV excitation.
Light-On LysoView™ 555 is a red fluorogenic lysosome dye with pH-dependent fluorescence. Light-On LysoView™ dye is unique among commercially available lysosomotropic dyes in that its fluorescence in cells is activated by exposure to UV excitation.
TMRE, 2 mM in DMSO
TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.
TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.
4-Di-1-ASP
4-Di-1-ASP is a styryl dye stains mitochondria of live cells. It has also been used to stain glioma cells in living brain tissues.
4-Di-1-ASP is a styryl dye stains mitochondria of live cells. It has also been used to stain glioma cells in living brain tissues.
JC-1 (chloride salt)
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine chloride) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion.JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine chloride) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion.JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
Rhodamine 123
Rhodamine 123 is a popular green fluorescent mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. It is widely used in flow cytometry studies involving mitochondrial membrane potential.
Rhodamine 123 is a popular green fluorescent mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. It is widely used in flow cytometry studies involving mitochondrial membrane potential.
DiOC6(3)
DiOC6(3) (3,3′-Dihexyloxacarbocyanine,iodide) is a green fluorescent membrane dye that has been used to stain the ER in both live and fixed cells (1,2). The dye has also been used to study structural interactions and dynamics of the ER in neurons (3,4) and yeast (5).
DiOC6(3) (3,3′-Dihexyloxacarbocyanine,iodide) is a green fluorescent membrane dye that has been used to stain the ER in both live and fixed cells (1,2). The dye has also been used to study structural interactions and dynamics of the ER in neurons (3,4) and yeast (5).
JC-1 (iodide salt)
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine, iodide) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine, iodide) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
Nonyl Acridine Orange (NAO)
NAO is a mitochondrial dye whose staining is not dependent on mitochondrial membrane potential,unlike JC-1 (70011) and Rhodamine 123 (70010).
NAO is a mitochondrial dye whose staining is not dependent on mitochondrial membrane potential,unlike JC-1 (70011) and Rhodamine 123 (70010).
TMRM
TMRM (Tetramethylrhodamine methyl ester, perchlorate) and TMRE ( 70016) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.
TMRM (Tetramethylrhodamine methyl ester, perchlorate) and TMRE ( 70016) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.
TMRE
TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.
TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.
DiIC1(5) (1,1′-dimethyl-3,3,3′,3′-tetramethylindodicarbocyanine, iodide)
The carbocyanine dye DiIC1(5) has been used to measure mitochondrial membrane potential in apoptotic cells. Loss of membrane potential in apoptotic cells is reflected by a decrease of fluorescence signal in the infrared channel.
The carbocyanine dye DiIC1(5) has been used to measure mitochondrial membrane potential in apoptotic cells. Loss of membrane potential in apoptotic cells is reflected by a decrease of fluorescence signal in the infrared channel.
Tetrabromorhodamine 123, bromide
Tetrabromorhodamine 123 can be used to generate singlet oxygen (1O2) in mitochondrial membranes (1,2). The dye has a quantum yield for singlet oxygen generation of 0.65-0.7 and is particularly toxic to carcinoma cells.
Tetrabromorhodamine 123 can be used to generate singlet oxygen (1O2) in mitochondrial membranes (1,2). The dye has a quantum yield for singlet oxygen generation of 0.65-0.7 and is particularly toxic to carcinoma cells.
NBD C6-Ceramide
NBD C6-ceramide (6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine) has been used for following sphingolipid metabolism in cells, and as a selective stain for the Golgi apparatus in live and fixed cells.
NBD C6-ceramide (6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine) has been used for following sphingolipid metabolism in cells, and as a selective stain for the Golgi apparatus in live and fixed cells.
NucView® 488 and MitoView™ 633 Apoptosis Assay Kit
This kit contains the NucView®488 Caspase-3 Substrate and the MitoView™633 mitochondrial dye. The kit provides a convenient tool for profiling apoptotic cells based on caspase-3 activity and changes in the mitochondrial membrane potential using either fluorescence microscopy or flow cytometry.
This kit contains the NucView®488 Caspase-3 Substrate and the MitoView™633 mitochondrial dye. The kit provides a convenient tool for profiling apoptotic cells based on caspase-3 activity and changes in the mitochondrial membrane potential using either fluorescence microscopy or flow cytometry.