Dyes for Mitochondria & Other Organelles
Biotium sells a range of dyes to stain organelles such as the mitochondria and lysosomes in cells. Many of the mitochondria dyes are dependent on mitochondrial membrane potential and can therefore be used to monitor membrane potential changes that occur during processes such as apoptosis.
MitoView™ Dyes stain the mitochondria in living cells. They come in 3 colors, including both membrane potential-dependent and -independent options. We also offer a wide selection of classical potential-dependent mitochondrial dyes such as JC-1, TMRE, TMRM.
LysoView™ Dyes stain the lysosomes in living cells. Available in 5 colors, plus a novel UV-inducible version.
LipidSpot™ stains lipid droplets, cytoplasmic organelles involved in the storage and regulation of triglycerides and cholesterol esters.
LipidSpot™ Lipid Droplet Stains
LipidSpot™ Dyes rapidly stains lipid droplets in live cells or fixed cells, with no wash step required. Available with green or red/far-red fluorescence.
LipidSpot™ Dyes rapidly stains lipid droplets in live cells or fixed cells, with no wash step required. Available with green or red/far-red fluorescence.
LysoView™ Dyes
LysoView™ dyes label lysosomes in live cells, and are available with blue, green, visible red, and far-red fluorescence, with dye options for super-resolution imaging by SIM and STED.
LysoView™ dyes label lysosomes in live cells, and are available with blue, green, visible red, and far-red fluorescence, with dye options for super-resolution imaging by SIM and STED.
JC-1 Mitochondrial Membrane Potential Detection Kit
JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells.
JC-1 Mitochondrial Membrane Potential Detection Kit is used to measure mitochondrial membrane potential changes in cells.
Light-on LysoView™ 555
Light-On LysoView™ 555 is a red fluorogenic lysosome dye with pH-dependent fluorescence. Light-On LysoView™ dye is unique among commercially available lysosomotropic dyes in that its fluorescence in cells is activated by exposure to UV excitation.
Light-On LysoView™ 555 is a red fluorogenic lysosome dye with pH-dependent fluorescence. Light-On LysoView™ dye is unique among commercially available lysosomotropic dyes in that its fluorescence in cells is activated by exposure to UV excitation.
MitoView™ Mitochondrial Dyes
Fluorogenic mitochondrial stains for live cells that rapidly accumulate in mitochondria and can be imaged without washing.
Fluorogenic mitochondrial stains for live cells that rapidly accumulate in mitochondria and can be imaged without washing.
4-Di-1-ASP
4-Di-1-ASP is a styryl dye that stains mitochondria of live cells. It has also been used to stain glioma cells in living brain tissues.
4-Di-1-ASP is a styryl dye that stains mitochondria of live cells. It has also been used to stain glioma cells in living brain tissues.
DASPEI
DASPEI (2-(4-(Dimethylamino)styryl)-N-ethylpyridinium iodide) is used to stain mitochondria in live cells.
DASPEI (2-(4-(Dimethylamino)styryl)-N-ethylpyridinium iodide) is used to stain mitochondria in live cells.
Dihydrorhodamine 123
Dihydrorhodamine 123 is the reduced form of rhodamine 123 (70010), which is a commonly used fluorescent mitochondrial dye.
Dihydrorhodamine 123 is the reduced form of rhodamine 123 (70010), which is a commonly used fluorescent mitochondrial dye.
Dihydrorhodamine 123, Dihydrochloride Salt
Dihydrorhodamine 123 dihydrochloride is functionally equivalent to dihydrorhodamine 123 (10055) but with increased stability toward air oxidation and light during storage.
Dihydrorhodamine 123 dihydrochloride is functionally equivalent to dihydrorhodamine 123 (10055) but with increased stability toward air oxidation and light during storage.
DiIC1(5) (1,1′-dimethyl-3,3,3′,3′-tetramethylindodicarbocyanine, iodide)
The carbocyanine dye DiIC1(5) has been used to measure mitochondrial membrane potential in apoptotic cells. Loss of membrane potential in apoptotic cells is reflected by a decrease of fluorescence signal in the infrared channel.
The carbocyanine dye DiIC1(5) has been used to measure mitochondrial membrane potential in apoptotic cells. Loss of membrane potential in apoptotic cells is reflected by a decrease of fluorescence signal in the infrared channel.
JC-1 (chloride salt)
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine chloride) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion.JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine chloride) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion.JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
JC-1 (iodide salt)
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine, iodide) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
JC-1 (5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine, iodide) is a mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. JC-1monomer is in equilibrium with so-called J-aggregates, which are favored at higher dye concentration or higher mitochondrial membrane potential.
NBD C6-Ceramide
NBD C6-ceramide (6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine) has been used for following sphingolipid metabolism in cells, and as a selective stain for the Golgi apparatus in live and fixed cells.
NBD C6-ceramide (6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine) has been used for following sphingolipid metabolism in cells, and as a selective stain for the Golgi apparatus in live and fixed cells.
Nonyl Acridine Orange (NAO)
NAO is a green fluorescent mitochondrial dye whose staining is not dependent on mitochondrial membrane potential.
NAO is a green fluorescent mitochondrial dye whose staining is not dependent on mitochondrial membrane potential.
Rhodamine 123
Rhodamine 123 is a popular green fluorescent mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. It is widely used in flow cytometry studies involving mitochondrial membrane potential.
Rhodamine 123 is a popular green fluorescent mitochondrial dye that stains mitochondria in living cells in a membrane potential-dependent fashion. It is widely used in flow cytometry studies involving mitochondrial membrane potential.
Tetrabromorhodamine 123, bromide
Tetrabromorhodamine 123 can be used to generate singlet oxygen (1O2) in mitochondrial membranes (1,2). The dye has a quantum yield for singlet oxygen generation of 0.65-0.7 and is particularly toxic to carcinoma cells.
Tetrabromorhodamine 123 can be used to generate singlet oxygen (1O2) in mitochondrial membranes (1,2). The dye has a quantum yield for singlet oxygen generation of 0.65-0.7 and is particularly toxic to carcinoma cells.