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Protease Substrates

See below for fluorescent substrates for proteases such as caspases, peptidases, elastases, granzyme B, cathepsins, and others.

Caspase substrates include the novel, non-toxic, fluorogenic NucView® caspase-3 substrates, available in 3 colors.

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    Dual Apoptosis Assay with NucView® 488 Caspase-3 Substrate & Annexin V

    From: $341 Sizes: 50 assaysCatalog #: 30030, 30067, - 30073View allHide

    These kits provides two apoptosis markers, our novel NucView® 488 Caspase-3 Substrate and Annexin V conjugated with your choice of red or far-red dye. The kit is used for studying two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation.

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    These kits provides two apoptosis markers, our novel NucView® 488 Caspase-3 Substrate and Annexin V conjugated with your choice of red or far-red dye. The kit is used for studying two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation.

     

    NucView® 405 Caspase-3 Substrate, 1 mM in DMSO

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10405, - 10405-TView allHide

    NucView® 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView® 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    NucView® 405 Caspase-3 Substrate, 1 mM in PBS

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10407-T, - 10407View allHide

    NucView® 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView® 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    NucView® 488 and MitoView™ 633 Apoptosis Assay Kit

    From: $341 Sizes: 100 assaysCatalog #: 30062

    This kit contains the NucView®488 Caspase-3 Substrate and the MitoView™633 mitochondrial dye. The kit provides a convenient tool for profiling apoptotic cells based on caspase-3 activity and changes in the mitochondrial membrane potential using either fluorescence microscopy or flow cytometry.

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    100 assays
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    This kit contains the NucView®488 Caspase-3 Substrate and the MitoView™633 mitochondrial dye. The kit provides a convenient tool for profiling apoptotic cells based on caspase-3 activity and changes in the mitochondrial membrane potential using either fluorescence microscopy or flow cytometry.

     

    NucView® 488 and RedDot™ 2 Apoptosis and Necrosis Kit

    From: $299 Sizes: 100 assaysCatalog #: 30072

    NucView®488 and RedDot™2 Apoptosis/Necrosis Assay Kit contains NucView®488 Caspase-3 Substrate for detection of caspase-3/7 activity. The far-red dead-cell stain RedDot™2 is included for staining necrotic and late apoptotic cells that have compromised plasma membrane integrity.

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    100 assays
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    NucView®488 and RedDot™2 Apoptosis/Necrosis Assay Kit contains NucView®488 Caspase-3 Substrate for detection of caspase-3/7 activity. The far-red dead-cell stain RedDot™2 is included for staining necrotic and late apoptotic cells that have compromised plasma membrane integrity.

     

    NucView® 488 Caspase-3 Assay Kit for Live Cells

    From: $92 Sizes: Trial size (25 assays), 100 assaysCatalog #: 30029, - 30029-TView allHide

    NucView® 488 Caspase-3 substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3 activity within live cells in real time.

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    NucView® 488 Caspase-3 substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3 activity within live cells in real time.

     

    NucView® 488 Caspase-3 Enzyme Substrate, 1 mM in DMSO

    From: $63 Sizes: 10 uL, 100 uLCatalog #: 10402, - 10402-TView allHide

    NucView® 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

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    NucView® 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

     

    NucView® 488 Caspase-3 Enzyme Substrate, 1 mM in PBS

    From: $63 Sizes: 10 uL, 100 uLCatalog #: 10403, - 10403-TView allHide

    NucView® 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

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    NucView® 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

     

    NucView® 530 Caspase-3 Substrate, 1 mM in DMSO

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10406, - 10406-TView allHide

    NucView® 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView® 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    NucView® 530 Caspase-3 Substrate, 1 mM in PBS

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10408, - 10408-TView allHide

    NucView® 530 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView® 530 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    Caspase-3 DEVD-R110 Fluorometric and Colorimetric Assay Kit

    From: $139 Sizes: 25 assays, 100 assaysCatalog #: 30008-1, - 30008-2View allHide

    Caspase-3 is an active cell-death protease involved in the execution phase of apoptosis, during which cells undergo morphological changes such as DNA fragmentation, chromatin condensation and apoptotic body formation.

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    Caspase-3 is an active cell-death protease involved in the execution phase of apoptosis, during which cells undergo morphological changes such as DNA fragmentation, chromatin condensation and apoptotic body formation.

     

    Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit

    From: $46 Sizes: 10 assays, 100 assays, 1,000 assaysCatalog #: 30009-1, 30009-2, - 30009-3View allHide

    Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-3 activity by fluorescence in enzymatic reaction or mammalian cells.

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    Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-3 activity by fluorescence in enzymatic reaction or mammalian cells.

     

    Caspase-8 IETD-R110 Fluorometric and Colorimetric Assay Kit

    From: $139 Sizes: 25 assays, 100 assaysCatalog #: 30011-1, - 30011-2View allHide

    Caspase-8 is the most upstream caspase in the CD95/Fas apoptotic pathway and is activated by the signaling pathways for CD95/Fas and TNF. Caspase-8 Fluorometric and Colorimetric Assay Kit provides a simple assay system for fast and sensitive detection of caspase-8 activity either by fluorescence or absorbance.

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    25 assays
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    Caspase-8 is the most upstream caspase in the CD95/Fas apoptotic pathway and is activated by the signaling pathways for CD95/Fas and TNF. Caspase-8 Fluorometric and Colorimetric Assay Kit provides a simple assay system for fast and sensitive detection of caspase-8 activity either by fluorescence or absorbance.

     

    Caspase-8 IETD-R110 Fluorometric HTS Assay Kit

    From: $46 Sizes: 10 assays, 100 assays, 1,000 assaysCatalog #: 30012-1, 30012-2, - 30012-3View allHide

    Caspase-8 IETD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-8 activity by fluorescence in enzymatic reaction or mammalian cells.

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    Caspase-8 IETD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-8 activity by fluorescence in enzymatic reaction or mammalian cells.

     

    Ac-DEVD-AMC

    From: $210 Sizes: 5 mgCatalog #: 10202

    Ac-DEVD-AMC is a fluorogenic substrate for caspase 3 and can be used to continuously measure the activity of caspase-3 in cell extracts, using a fluorometer or fluorescence microplate reader. For real-time detection of caspase-3 activity in intact cells, see our novel NucView®488 Caspase-3 Assay Kit.

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    5 mg
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    Ac-DEVD-AMC is a fluorogenic substrate for caspase 3 and can be used to continuously measure the activity of caspase-3 in cell extracts, using a fluorometer or fluorescence microplate reader. For real-time detection of caspase-3 activity in intact cells, see our novel NucView®488 Caspase-3 Assay Kit.

     

    Ac-IETD-R110

    From: $243 Sizes: 5 mgCatalog #: 10207

    Z-IETD-R110 is a substrate for caspase-8, which is involved at the early stage of apoptosis, acting as an initiator of the caspase activation cascade.

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    5 mg
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    Z-IETD-R110 is a substrate for caspase-8, which is involved at the early stage of apoptosis, acting as an initiator of the caspase activation cascade.