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Protease Substrates

Showing 1–20 of 25 results

    Ac-DEVD-AMC

    From: $210 Sizes: 5 mgCatalog #: 10202

    Ac-DEVD-AMC is a fluorogenic substrate for caspase 3 and can be used to continuously measure the activity of caspase-3 in cell extracts, using a fluorometer or fluorescence microplate reader. For real-time detection of caspase-3 activity in intact cells, see our novel NucView™488 Caspase-3 Assay Kit.

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    Ac-DEVD-AMC is a fluorogenic substrate for caspase 3 and can be used to continuously measure the activity of caspase-3 in cell extracts, using a fluorometer or fluorescence microplate reader. For real-time detection of caspase-3 activity in intact cells, see our novel NucView™488 Caspase-3 Assay Kit.

     

    Ac-IETD-R110

    From: $243 Sizes: 5 mgCatalog #: 10207

    Z-IETD-R110 is a substrate for caspase-8, which is involved at the early stage of apoptosis, acting as an initiator of the caspase activation cascade.

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    Z-IETD-R110 is a substrate for caspase-8, which is involved at the early stage of apoptosis, acting as an initiator of the caspase activation cascade.

     

    BZAR

    Sizes: 5 mgCatalog #: 10205

    BZAR (Rhodamine 110, bis-(N-CBZ-L-arginine amide), dihydrochloride) is a substrate for serine proteases (1-5) and is also an inhibitor for quanidinobenzoatase. It is 50 to 100 times more sensitive than the AMC-based substrate.

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    BZAR (Rhodamine 110, bis-(N-CBZ-L-arginine amide), dihydrochloride) is a substrate for serine proteases (1-5) and is also an inhibitor for quanidinobenzoatase. It is 50 to 100 times more sensitive than the AMC-based substrate.

     

    BZiPAR

    Sizes: 5 mgCatalog #: 10208

    BZiPAR (Rhodamine 110, bis-(N-CBZ-L-isoleucyl-L-prolyl-L-arginine amide), dihydrochloride) is a substrate for trypsin (1,2). The substrate has been reported to enter live cells and be hydrolyzed by lysosomal proteases (3).

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    BZiPAR (Rhodamine 110, bis-(N-CBZ-L-isoleucyl-L-prolyl-L-arginine amide), dihydrochloride) is a substrate for trypsin (1,2). The substrate has been reported to enter live cells and be hydrolyzed by lysosomal proteases (3).

     

    Caspase-3 DEVD-R110 Fluorometric and Colorimetric Assay Kit

    From: $139 Sizes: 25 assays, 100 assaysCatalog #: 30008-1, - 30008-2View allHide

    Caspase-3 is an active cell-death protease involved in the execution phase of apoptosis, during which cells undergo morphological changes such as DNA fragmentation, chromatin condensation and apoptotic body formation.

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    Caspase-3 is an active cell-death protease involved in the execution phase of apoptosis, during which cells undergo morphological changes such as DNA fragmentation, chromatin condensation and apoptotic body formation.

     

    Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit

    From: $46 Sizes: 10 assays, 100 assays, 1,000 assaysCatalog #: 30009-1, 30009-2, - 30009-3View allHide

    Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-3 activity by fluorescence in enzymatic reaction or mammalian cells.

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    Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-3 activity by fluorescence in enzymatic reaction or mammalian cells.

     

    Caspase-8 IETD-R110 Fluorometric and Colorimetric Assay Kit

    From: $139 Sizes: 25 assays, 100 assaysCatalog #: 30011-1, - 30011-2View allHide

    Caspase-8 is the most upstream caspase in the CD95/Fas apoptotic pathway and is activated by the signaling pathways for CD95/Fas and TNF. Caspase-8 Fluorometric and Colorimetric Assay Kit provides a simple assay system for fast and sensitive detection of caspase-8 activity either by fluorescence or absorbance.

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    Caspase-8 is the most upstream caspase in the CD95/Fas apoptotic pathway and is activated by the signaling pathways for CD95/Fas and TNF. Caspase-8 Fluorometric and Colorimetric Assay Kit provides a simple assay system for fast and sensitive detection of caspase-8 activity either by fluorescence or absorbance.

     

    Caspase-8 IETD-R110 Fluorometric HTS Assay Kit

    From: $46 Sizes: 10 assays, 100 assays, 1,000 assaysCatalog #: 30012-1, 30012-2, - 30012-3View allHide

    Caspase-8 IETD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-8 activity by fluorescence in enzymatic reaction or mammalian cells.

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    Caspase-8 IETD-R110 Fluorometric HTS Assay Kit is specifically designed for HTS-based assays. The kit provides a homogenous assay system for fast and highly sensitive detection of caspase-8 activity by fluorescence in enzymatic reaction or mammalian cells.

     

    D2R

    Sizes: 2 mgCatalog #: 10210

    D2R

    D2R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D2R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts.

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    D2R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D2R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts.

     

    Dual Apoptosis Assay with NucView 488 Caspase-3 Substrate & Annexin V

    From: $341 Sizes: 50 assaysCatalog #: 30030, 30067, - 30073View allHide

    This kit provides two apoptosis markers, our novel NucView™ 488 Caspase-3 Substrate and Annexin V conjugated with your choice of red or far-red dye. The kit is used for studying two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation.

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    This kit provides two apoptosis markers, our novel NucView™ 488 Caspase-3 Substrate and Annexin V conjugated with your choice of red or far-red dye. The kit is used for studying two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation.

     

    NucView 405 Caspase-3 Substrate, 1 mM in DMSO

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10405, - 10405-TView allHide

    NucView™ 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView™ 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    NucView 405 Caspase-3 Substrate, 1 mM in PBS

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10407-T, - 10407View allHide

    NucView™ 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView™ 405 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    NucView 488 and MitoView 633 Apoptosis Assay Kit

    From: $341 Sizes: 100 assaysCatalog #: 30062

    This kit contains the NucView™488 Caspase-3 Substrate and the MitoView™633 mitochondrial dye. The kit provides a convenient tool for profiling apoptotic cells based on caspase-3 activity and changes in the mitochondrial membrane potential using either fluorescence microscopy or flow cytometry.

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    100 assays
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    This kit contains the NucView™488 Caspase-3 Substrate and the MitoView™633 mitochondrial dye. The kit provides a convenient tool for profiling apoptotic cells based on caspase-3 activity and changes in the mitochondrial membrane potential using either fluorescence microscopy or flow cytometry.

     

    NucView 488 and RedDot 2 Apoptosis and Necrosis Kit

    From: $299 Sizes: 100 assaysCatalog #: 30072

    NucView™488 and RedDot™2 Apoptosis/Necrosis Assay Kit contains NucView™488 Caspase-3 Substrate for detection of caspase-3/7 activity. The far-red dead-cell stain RedDot™2 is included for staining necrotic and late apoptotic cells that have compromised plasma membrane integrity.

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    NucView™488 and RedDot™2 Apoptosis/Necrosis Assay Kit contains NucView™488 Caspase-3 Substrate for detection of caspase-3/7 activity. The far-red dead-cell stain RedDot™2 is included for staining necrotic and late apoptotic cells that have compromised plasma membrane integrity.

     

    NucView 488 Caspase-3 Assay Kit for Live Cells

    From: $92 Sizes: Trial size (25 assays), 100 assaysCatalog #: 30029, - 30029-TView allHide

    NucView™ 488 Caspase-3 substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3 activity within live cells in real time.

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    NucView™ 488 Caspase-3 substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3 activity within live cells in real time.

     

    NucView 488 Caspase-3 Enzyme Substrate, 1 mM in DMSO

    From: $63 Sizes: 100 uL, 10 uLCatalog #: 10402, - 10402-TView allHide

    NucView™ 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

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    NucView™ 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

     

    NucView 488 Caspase-3 Enzyme Substrate, 1 mM in PBS

    From: $63 Sizes: 100 uL, 10 uLCatalog #: 10403, - 10403-TView allHide

    NucView™ 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

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    NucView™ 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.

     

    NucView 530 Caspase-3 Substrate, 1 mM in DMSO

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10406, - 10406-TView allHide

    NucView™ 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView™ 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    NucView 530 Caspase-3 Substrate, 1 mM in PBS

    From: $63 Sizes: Trial size (10 uL), 100 uLCatalog #: 10408, - 10408-TView allHide

    NucView™ 530 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

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    NucView™ 530 Caspase-3 Substrate, 1 mM in PBS, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.

     

    R110-PEG (Rhodamine 110-PEG)

    From: $176 Sizes: 5 mgCatalog #: 10225

    R110-PEG can be used as a reference standard for peptidase substrates based on the dye.

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    R110-PEG can be used as a reference standard for peptidase substrates based on the dye.