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Amine-Reactive Dyes

Succinimidyl esters (SE, also known as NHS esters) react with primary amines such as lysine residues in proteins. SE dyes are commonly used for labeling proteins and antibodies. The reaction requires basic pH for target amines to be reactive, and is usually performed in pH 8.3 sodium bicarbonate buffer.

We offer more than 25 colors of our bright and photostable CF® Dye SE and easy-to-use CF® Dye Labeling Kits, as well as a wide variety of other amine-reactive dyes and biotinylation reagents below. Biotium’s CF dye SE are more resistant to hydrolyis than other SE, resulting in excellent reaction efficiency.

Showing 1–16 of 55 results

    CF® Dye & Biotin SE Protein Labeling Kits

    From: $383 Sizes: 3 labelingsCatalog #: 92208, 92209, 92210, 92211, 92212, 92213, 92214, 92215, 92216, 92217, 92218, 92219, 92220, 92221, 92222, 92223, 92224, 92225, 92226, - 92228View allHide

    This kit contains everything you need to label antibodies or other proteins with a fluorescent CF® dye succinimidyl ester (CF dye SE) or biotin succinimidyl ester (biotin SE). Each kit contains reagents for three labeling reactions of up to 1 mg protein per reaction.

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    This kit contains everything you need to label antibodies or other proteins with a fluorescent CF® dye succinimidyl ester (CF dye SE) or biotin succinimidyl ester (biotin SE). Each kit contains reagents for three labeling reactions of up to 1 mg protein per reaction.

     

    VivoBrite™ Rapid Antibody Labeling Kits for Small Animal In Vivo Imaging

    From: $415 Sizes: 3 labelingsCatalog #: 92160, 92161, 92162, - 92163View allHide

    This labeling kit comprises our superior near-IR amine-reactive CF® dye and other components necessary for carrying out antibody labeling and purification. It’s available with the following CF® dyes: CF®680, CF®750, CF®770, and CF®790.

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    This labeling kit comprises our superior near-IR amine-reactive CF® dye and other components necessary for carrying out antibody labeling and purification. It’s available with the following CF® dyes: CF®680, CF®750, CF®770, and CF®790.

     

    CBQCA

    From: $263 Sizes: 10 mgCatalog #: 90070

    CBQCA (3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) reacts specifically with primary amines to form conjugates that can be analyzed by electrophoretic or chromatographic methods. CBQCA also reacts with hydrophilic peptides and amino sugars.

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    CBQCA (3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) reacts specifically with primary amines to form conjugates that can be analyzed by electrophoretic or chromatographic methods. CBQCA also reacts with hydrophilic peptides and amino sugars.

     

    Sulforhodamine B-PEO8 SE

    From: $116 Sizes: 1 mgCatalog #: 90101

    Sulforhodamine B-PEO<sub>8</sub> SE (Sulforhodamine B-PEO8-propionic acid succinimydyl ester) has an approximately 32 Angstrom water-soluble PEG spacer that separates the dye from the amine-reactive SE group.

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    Sulforhodamine B-PEO<sub>8</sub> SE (Sulforhodamine B-PEO8-propionic acid succinimydyl ester) has an approximately 32 Angstrom water-soluble PEG spacer that separates the dye from the amine-reactive SE group.

     

    Sulforhodamine 101-PEO12 SE

    From: $127 Sizes: 1 mgCatalog #: 90100

    SR101-PEO12 SE (Sulforhodamine 101-PEO12-propionic acid succinimydyl ester; Texas Red-PEO12 SE) has an approximately 47 Angstrom water-soluble PEG spacer that separates the dye from the amine-reactive SE group.

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    SR101-PEO12 SE (Sulforhodamine 101-PEO12-propionic acid succinimydyl ester; Texas Red-PEO12 SE) has an approximately 47 Angstrom water-soluble PEG spacer that separates the dye from the amine-reactive SE group.

     

    Sulforhodamine 101-PEO8 SE

    From: $116 Sizes: 1 mgCatalog #: 90099

    SR101-PEO8 SE (Sulforhodamine 101-PEO8-propionic acid succinimydyl ester; Texas Red-PEO8 SE) has an approximately 32 Angstrom water-soluble PEG spacer that separates the dye from the amine-reactive SE group.

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    SR101-PEO8 SE (Sulforhodamine 101-PEO8-propionic acid succinimydyl ester; Texas Red-PEO8 SE) has an approximately 32 Angstrom water-soluble PEG spacer that separates the dye from the amine-reactive SE group.

     

    Carboxyrhodamine 110-PEO4, SE, 5 isomer

    From: $386 Sizes: 5 mgCatalog #: 90081

    5-CR110-PEO4 SE (full name: 5-Carboxyrhodamine 110-PEO4-propionate, succinimidyl ester, single isomer) is an excellent green fluorescent rhodamine dye for labeling amines. The dye has better solubility than the parent dye 5-CR110 SE and its long PEG spacer should reduce any steric effect of the dye on the molecule to be labeled.

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    5-CR110-PEO4 SE (full name: 5-Carboxyrhodamine 110-PEO4-propionate, succinimidyl ester, single isomer) is an excellent green fluorescent rhodamine dye for labeling amines. The dye has better solubility than the parent dye 5-CR110 SE and its long PEG spacer should reduce any steric effect of the dye on the molecule to be labeled.

     

    Carboxyrhodamine 110 succinimidyl ester, 6-isomer

    From: $436 Sizes: 5 mgCatalog #: 90031

    Amine-reactive form of single isomer carboxyrhodamine 110. For certain applications, the dye is preferred over the corresponding 6-carboxyfluorescein because of its exceptional photostability and fluorescence insensitivity to pH change (4-9).

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    Amine-reactive form of single isomer carboxyrhodamine 110. For certain applications, the dye is preferred over the corresponding 6-carboxyfluorescein because of its exceptional photostability and fluorescence insensitivity to pH change (4-9).

     

    Carboxyrhodamine 110 succinimidyl ester, 5-isomer

    From: $436 Sizes: 5 mgCatalog #: 90030

    Amine-reactive form of single isomer carboxyrhodamine 110, useful in DNA sequencing. For many single-dye-labeling applications, the dye is preferred over other green fluorescent dyes including fluorescein and Alexa 488 because of its exceptional photostability and fluorescence insensitivity to pH (4-9).

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    Amine-reactive form of single isomer carboxyrhodamine 110, useful in DNA sequencing. For many single-dye-labeling applications, the dye is preferred over other green fluorescent dyes including fluorescein and Alexa 488 because of its exceptional photostability and fluorescence insensitivity to pH (4-9).

     

    Carboxyrhodamine 110-X succinimidyl ester, 6-isomer

    From: $436 Sizes: 5 mgCatalog #: 90015

    6-CR110-X, SE (full name: 6-Carboxyrhodamine 110-X, succinimidyl ester) is the amine-reactive form of 6-carboxyrhodamine 110 with a 6-carbon spacer.

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    6-CR110-X, SE (full name: 6-Carboxyrhodamine 110-X, succinimidyl ester) is the amine-reactive form of 6-carboxyrhodamine 110 with a 6-carbon spacer.

     

    Carboxyrhodamine 110-X succinimidyl ester, 5-isomer

    From: $436 Sizes: 5 mgCatalog #: 90014

    5-CR110-X, SE (full name: 5-Carboxyrhodamine 110-X, succinimidyl ester) is the amine-reactive form of 5-carboxyrhodamine 110 with a 6-carbon spacer.

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    5-CR110-X, SE (full name: 5-Carboxyrhodamine 110-X, succinimidyl ester) is the amine-reactive form of 5-carboxyrhodamine 110 with a 6-carbon spacer.

     

    ROX, SE, 6 isomer in DMSO

    From: $231 Sizes: 100 uLCatalog #: 90098

    6-ROX, SE is the amine-reactive form of 6-ROX single isomer (90037) dissolved in anhydrous DMSO, suitable for labeling oligonucleotides.

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    6-ROX, SE is the amine-reactive form of 6-ROX single isomer (90037) dissolved in anhydrous DMSO, suitable for labeling oligonucleotides.

     

    TAMRA SE, 6 isomer in DMSO

    From: $231 Sizes: 100 uLCatalog #: 90097

    6-TAMRA SE (full name: 6-Carboxytetramethylrhodamine succinimidyl ester) is the amine-reactive form of 6-TAMRA single isomer (90035).

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    6-TAMRA SE (full name: 6-Carboxytetramethylrhodamine succinimidyl ester) is the amine-reactive form of 6-TAMRA single isomer (90035).

     

    SFX, 6 isomer

    From: $105 Sizes: 5 mgCatalog #: 90096

    6-SFX (full name: 6-(Fluorescein-6-carboxamido)hexanoic acid, succinimidyl ester, single isomer) has a 6-atom aminohexanoyl spacer group that separates the fluorescein dye and the amine-reactive group.

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    6-SFX (full name: 6-(Fluorescein-6-carboxamido)hexanoic acid, succinimidyl ester, single isomer) has a 6-atom aminohexanoyl spacer group that separates the fluorescein dye and the amine-reactive group.

     

    SFX, 5 isomer

    From: $105 Sizes: 5 mgCatalog #: 90095

    5-SFX (full name: 6-(Fluorescein-5-carboxamido)hexanoic acid, succinimidyl ester, single isomer) has a 6-atom aminohexanoyl spacer group that separates the fluorescein dye and the amine-reactive group.

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    5-SFX (full name: 6-(Fluorescein-5-carboxamido)hexanoic acid, succinimidyl ester, single isomer) has a 6-atom aminohexanoyl spacer group that separates the fluorescein dye and the amine-reactive group.

     

    FAM-PEO12 SE, 5 isomer

    From: $116 Sizes: 1 mgCatalog #: 90093

    5-FAM-PEO12 SE (full name: 5-Carboxyfluorescein-PEO12 propionate succinimidyl ester) has an approximately 47 Angstrom water-soluble PEG spacer that separates fluorescein and the amine-reactive SE group.

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    5-FAM-PEO12 SE (full name: 5-Carboxyfluorescein-PEO12 propionate succinimidyl ester) has an approximately 47 Angstrom water-soluble PEG spacer that separates fluorescein and the amine-reactive SE group.