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Calcium Indicators & Chelators

Biotium offers a wide range of calcium indicator dyes, including Fluo-4 AM Ester, a bright and cell permeable dye that is used for high-throughput screening.

The calcium indicator dyes vary in their calcium dissociation constant (Kd), color and brightness. The AM ester versions are cell permeable, and hydrolyzed by intracellular esterases to release the fluorescent dye. See our complete selection of Calcium & Other Ion Indicators, or download the Ion Indicator Brochure to learn more.

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    Product

    Fluo-4 AM Ester

    From: $322 Sizes: 10 x 50 ugCatalog #: 50018

    Membrane-permeant form of Fluo-4 calcium indicator.

     
    Product

    Fluo-3, AM Ester

    From: $262 Sizes: 10 x 100 ug, 1 mg, 20 x 50 ugCatalog #:
    50013
    , 50014, - 50016View allHide

    Membrane-permeant AM ester form of Fluo-3 that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading.

     
    Product

    DMNP-EDTA (Caged Calcium), AM Ester

    From: $138 Sizes: 1 mg, 5 mgCatalog #:
    50051-5mg
    , - 50051-1mgView allHide

    The membrane-permeant form of DMNP-EDTA (also known as DM-Nitrophen™), a photolyzable calcium chelator that can be used to release a pulse of calcium when exposed to light.

     
    Product

    Mag-Fluo-4, AM Ester

    From: $381 Sizes: 10 x 50 ugCatalog #: 50048

    Membrane-permeant AM ester form of Mag-Fluo-4, a fluorescent magnesium and calcium ion indicator that is an analog of Fluo-4.

     
    Product

    Mag-Fluo-4, Tetrapotassium Salt

    From: $309 Sizes: 500 ugCatalog #: 50047

    Membrane-impermeant form of Mag-Fluo-4, a fluorescent magnesium and calcium ion indicator that is an analog of Fluo-4.

     
    Product

    Fluo-4, pentapotassium salt

    From: $247 Sizes: 0.5 mgCatalog #: 50019

    Fluo-4, pentapotassium is membrane-impermeant calcium indicator. It can be loaded into cells via microinjection or scrape loading.

     
    Product

    5,5′-Difluoro BAPTA, Tetrapotassium Salt

    From: $268 Sizes: 100 mgCatalog #: 50006

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    5,5′-Dibromo BAPTA, Tetrapotassium Salt

    From: $199 Sizes: 100 mgCatalog #: 50004

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    5,5′-Difluoro BAPTA, AM Ester

    From: $329 Sizes: 25 mgCatalog #: 50005

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    BAPTA, Tetrasodium Salt

    From: $262 Sizes: 1 gCatalog #: 50003

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    BAPTA, Tetrapotassium Salt

    From: $262 Sizes: 1 gCatalog #: 50002

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    Rhod-590, Tripotassium Salt

    From: $357 Sizes: 500 ugCatalog #: 50026

    Membrane-impermeant calcium indicator that can be loaded into cells via microinjection or scrape loading. For the membrane-permeable AM ester form of Rhod-590, see 50025.

     
    Product

    Rhod-590 AM Ester

    From: $448 Sizes: 10 x 50 ugCatalog #: 50025

    Membrane-permeant form of Rhod-590 that can be loaded into cells via incubation.

     
    Product

    Pluronic® F-127

    From: $30 Sizes: 1 gCatalog #: 59000

    Nonionic detergent useful for solubilizing hydrophobic compounds to facilitate cell loading.

     
    Product

    Pluronic® F-127, 10% in H2O

    From: $76 Sizes: 30 mLCatalog #: 59005

    Ready-to-use solution of Pluronic® F-127, a nonionic detergent useful for solubilizing hydrophobic compounds like AM esters of calcium indicator dyes to facilitate cell loading.

     
    Product

    Ionomycin, Calcium Salt

    From: $212 Sizes: 1 mgCatalog #: 59007

    Ionomycin is commonly used to modify intracellular calcium concentrations and to calibrate fluorescent calcium indicators. It is also known for its antiproliferative effects.