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Can CellBrite® or MemBrite® Stains be used to stain exosomes/extracellular vesicles?

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CellBrite® Cytoplasmic Membrane Dyes are too prone to aggregation to efficiently stain EVs. Some of the CellBrite® Fix, MemBrite® Fix, and CellBrite® Steady dye options have been reported for this application, however we do not recommend them. For optimal staining of exosome membranes we recommend our ExoBrite™ True EV Membrane Stains, which are novel lipophilic membrane dyes specifically designed and optimized for efficient staining of EV membranes with minimal dye aggregation. See our Extracellular Vesicle Research page for more information about our complete line of EV stains and antibodies.


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