Dead cell stains
Dead cell stains are membrane-impermeant dyes that are excluded by viable cells, but stain necrotic or late apoptotic cells with damaged plasma membranes. Many of our dead cell stains are fluorogenic nucleic acid dyes that only fluoresce when bound to DNA or RNA inside dead cells, eliminating the need to wash before detection. See our full selection of nuclear stains on our Cellular Stains Technology Page.
Most DNA binding dead-cell stains are not fixable, meaning that the dyes will diffuse from stained cells to unstained cells after fixation, resulting in lower signal and higher background. Our Live-or-Dye™ Fixable Viability Stains are membrane-impermeant reactive dyes that covalently label dead cells. While these stains require washing, the staining can withstand fixation and permeabilization for subsequent IF staining. They also are useful for excluding dead cells from flow cytometry analysis of cell surface staining. See our complete selection of Apoptosis & Viability Stains.
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Live-or-Dye NucFix™ Red Staining Kit
Live-or-Dye NucFix™ Red is a unique, cell membrane impermeable dye that specifically stains the nuclei of dead cells.
Live-or-Dye NucFix™ Red is a unique, cell membrane impermeable dye that specifically stains the nuclei of dead cells.
Live-or-Dye™ Fixable Viability Staining Kits
Live-or-Dye™ Fixable Viability Staining Kits are designed for discrimination between live and dead cells during flow cytometry. Live/dead stains are useful probes to include when analyzing cell surface protein expression by flow cytometry, because they allow intracellular fluorescence signal from dead cells with permeable plasma membranes to be excluded from analysis.
Live-or-Dye™ Fixable Viability Staining Kits are designed for discrimination between live and dead cells during flow cytometry. Live/dead stains are useful probes to include when analyzing cell surface protein expression by flow cytometry, because they allow intracellular fluorescence signal from dead cells with permeable plasma membranes to be excluded from analysis.
NucSpot® 470 Nuclear Stain, 1000X in DMSO
NucSpot® 470 is cell membrane-impermeant, nuclear-specific green fluorescent DNA stain for the FITC channel.
NucSpot® 470 is cell membrane-impermeant, nuclear-specific green fluorescent DNA stain for the FITC channel.
RedDot™2 Far-Red Nuclear Stain, 200X in DMSO
RedDot™2 is a far-red cell membrane-impermeable nuclear dye similar to Draq7™, with excitation and emission at 665/695 nm. The dye is ideal for specifically staining the nuclei of dead cells with minimal cytoplasmic RNA staining.
RedDot™2 is a far-red cell membrane-impermeable nuclear dye similar to Draq7™, with excitation and emission at 665/695 nm. The dye is ideal for specifically staining the nuclei of dead cells with minimal cytoplasmic RNA staining.
Ethidium Homodimer III (EthD-III)
Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.
Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.
Ethidium Homodimer III (EthD-III), 1 mM in DMSO
Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.
Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.
Oxazole Yellow, 1mM in DMSO
Oxazole yellow, also know as YO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 491/509 nm when bound to nucleic acids. Oxazole yellow is also used to identify apoptotic cells. Supplied at 1 mM in DMSO.
Oxazole yellow, also know as YO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 491/509 nm when bound to nucleic acids. Oxazole yellow is also used to identify apoptotic cells. Supplied at 1 mM in DMSO.
Thiazole Red Homodimer, 1mM in DMSO
Thiazole red homodimer (TRhD), also know as TOTO-3, is a cell-impermeant, high-affinity nucleic acid stain based upon a symmetric cyanine dye dimer that is essentially nonfluorescent in the absence of nucleic acids that exhibits excitation/emission maxima ~642/660 nm when bound to nucleic acids.
Thiazole red homodimer (TRhD), also know as TOTO-3, is a cell-impermeant, high-affinity nucleic acid stain based upon a symmetric cyanine dye dimer that is essentially nonfluorescent in the absence of nucleic acids that exhibits excitation/emission maxima ~642/660 nm when bound to nucleic acids.
Thiazole Red, 1mM in DMSO
Thiazole red, also known as TO-PRO-3, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima ~642/661 nm when bound to nucleic acids.
Thiazole red, also known as TO-PRO-3, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima ~642/661 nm when bound to nucleic acids.
TO iodide (515/531), 1 mM in DMSO
TO iodide, also know as TO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 515/531 nm when bound to nucleic acids.
TO iodide, also know as TO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 515/531 nm when bound to nucleic acids.
7-AAD
7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.
7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.
7-AAD Solution, 1 mg/mL
7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.
7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.
Ethidium Homodimer I, 2 mM in DMSO
Ethidium Homodimer I, first developed by Dr. Le Pecq and his colleagues, is a high affinity fluorescent nucleic acid stain.
Ethidium Homodimer I, first developed by Dr. Le Pecq and his colleagues, is a high affinity fluorescent nucleic acid stain.
Propidium Iodide (PI)
Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.
Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.
Propidium Iodide Buffer (50 ug/mL)
Propidium Iodide is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.
Propidium Iodide is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.
Propidium Iodide, 1 mg/mL in Water
Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.
Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.