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Dead cell stains

Dead cell stains are membrane-impermeant dyes that are excluded by viable cells, but stain necrotic or late apoptotic cells with damaged plasma membranes. Many of our dead cell stains are fluorogenic nucleic acid dyes that only fluoresce when bound to DNA or RNA inside dead cells, eliminating the need to wash before detection. See our full selection of nuclear stains on our Cellular Stains Technology Page.

Most DNA binding dead-cell stains are not fixable, meaning that the dyes will diffuse from stained cells to unstained cells after fixation, resulting in lower signal and higher background. Our Live-or-Dye™ Fixable Viability Stains are membrane-impermeant reactive dyes that covalently label dead cells. While these stains require washing, the staining can withstand fixation and permeabilization for subsequent IF staining. They also are useful for excluding dead cells from flow cytometry analysis of cell surface staining. See our complete selection of Apoptosis & Viability Stains.

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    Live-or-Dye NucFix™ Red Staining Kit

    From: $60 Sizes: 50 assays, 200 assaysCatalog #: 32010, - 32010-TView allHide

    Live-or-Dye NucFix™ Red is a unique, cell membrane impermeable dye that specifically stains the nuclei of dead cells.

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    Live-or-Dye NucFix™ Red is a unique, cell membrane impermeable dye that specifically stains the nuclei of dead cells.

     

    Live-or-Dye™ Fixable Viability Staining Kits

    From: $63 Sizes: 50 assays, 200 assaysCatalog #: 32002-T, 32003-T, 32009-T, 32004-T, 32005-T, 32006-T, 32007-T, 32008-T, 32002, 32003, 32009, 32004, 32005, 32006, 32007, - 32008View allHide

    Live-or-Dye™ Fixable Viability Staining Kits are designed for discrimination between live and dead cells during flow cytometry. Live/dead stains are useful probes to include when analyzing cell surface protein expression by flow cytometry, because they allow intracellular fluorescence signal from dead cells with permeable plasma membranes to be excluded from analysis.

    Excitation/Emission
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    Live-or-Dye™ Fixable Viability Staining Kits are designed for discrimination between live and dead cells during flow cytometry. Live/dead stains are useful probes to include when analyzing cell surface protein expression by flow cytometry, because they allow intracellular fluorescence signal from dead cells with permeable plasma membranes to be excluded from analysis.

     

    NucSpot® 470 Nuclear Stain, 1000X in DMSO

    From: $50 Sizes: 20 uL, 200 uLCatalog #: 40083-T, - 40083View allHide

    NucSpot® 470 is cell membrane-impermeant, nuclear-specific green fluorescent DNA stain for the FITC channel.

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    NucSpot® 470 is cell membrane-impermeant, nuclear-specific green fluorescent DNA stain for the FITC channel.

     

    RedDot™2 Far-Red Nuclear Stain, 200X in DMSO

    From: $68 Sizes: 25 uL (15-20 tests, trial size), 250 uL (150-200 tests), 1 mL (600-1000 tests)Catalog #: 40061, 40061-1, - 40061-TView allHide

    RedDot™2 is a far-red cell membrane-impermeable nuclear dye similar to Draq7™, with excitation and emission at 665/695 nm. The dye is ideal for specifically staining the nuclei of dead cells with minimal cytoplasmic RNA staining.

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    RedDot™2 is a far-red cell membrane-impermeable nuclear dye similar to Draq7™, with excitation and emission at 665/695 nm. The dye is ideal for specifically staining the nuclei of dead cells with minimal cytoplasmic RNA staining.

     

    Ethidium Homodimer III (EthD-III)

    From: $242 Sizes: 1 mgCatalog #: 40050

    Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.

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    Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.

     

    Ethidium Homodimer III (EthD-III), 1 mM in DMSO

    From: $236 Sizes: 200 uLCatalog #: 40051

    Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.

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    Ethidium Homodimer III was developed by Biotium as an alternative to Ethidium Homodimer I. It has absorption and emission spectra similar to those of Ethidium Homodimer I, but stains DNA 45% brighter.

     

    Oxazole Yellow, 1mM in DMSO

    From: $265 Sizes: 1 mLCatalog #: 40089

    Oxazole yellow, also know as YO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 491/509 nm when bound to nucleic acids. Oxazole yellow is also used to identify apoptotic cells. Supplied at 1 mM in DMSO.

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    Oxazole yellow, also know as YO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 491/509 nm when bound to nucleic acids. Oxazole yellow is also used to identify apoptotic cells. Supplied at 1 mM in DMSO.

     

    Thiazole Red Homodimer, 1mM in DMSO

    From: $275 Sizes: 200 uLCatalog #: 40080

    Thiazole red homodimer (TRhD), also know as TOTO-3, is a cell-impermeant, high-affinity nucleic acid stain based upon a symmetric cyanine dye dimer that is essentially nonfluorescent in the absence of nucleic acids that exhibits excitation/emission maxima ~642/660 nm when bound to nucleic acids.

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    Thiazole red homodimer (TRhD), also know as TOTO-3, is a cell-impermeant, high-affinity nucleic acid stain based upon a symmetric cyanine dye dimer that is essentially nonfluorescent in the absence of nucleic acids that exhibits excitation/emission maxima ~642/660 nm when bound to nucleic acids.

     

    Thiazole Red, 1mM in DMSO

    From: $250 Sizes: 1 mLCatalog #: 40087

    Thiazole red, also known as TO-PRO-3, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima ~642/661 nm when bound to nucleic acids.

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    Thiazole red, also known as TO-PRO-3, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima ~642/661 nm when bound to nucleic acids.

     

    TO iodide (515/531), 1 mM in DMSO

    From: $235 Sizes: 1 mLCatalog #: 40088

    TO iodide, also know as TO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 515/531 nm when bound to nucleic acids.

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    TO iodide, also know as TO-PRO-1, is a cell-impermeant, high-affinity carbocyanine monomeric nucleic acid stain that is essentially nonfluorescent in the absence of nucleic acids but exhibits excitation/emission maxima 515/531 nm when bound to nucleic acids.

     

    7-AAD

    From: $110 Sizes: 1 mgCatalog #: 40037

    7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.

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    7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.

     

    7-AAD Solution, 1 mg/mL

    From: $150 Sizes: 1 mLCatalog #: 40084

    7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.

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    7-AAD (7-aminoactinomycin D) is a fluorescent DNA binding dye that is membrane impermeant and therefore generally excluded from viable cells.

     

    Ethidium Homodimer I, 2 mM in DMSO

    From: $186 Sizes: 0.5 mLCatalog #: 40014

    Ethidium Homodimer I, first developed by Dr. Le Pecq and his colleagues, is a high affinity fluorescent nucleic acid stain.

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    Ethidium Homodimer I, first developed by Dr. Le Pecq and his colleagues, is a high affinity fluorescent nucleic acid stain.

     

    Propidium Iodide (PI)

    From: $70 Sizes: 100 mgCatalog #: 40016

    Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.

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    100 mg
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    Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.

     

    Propidium Iodide Buffer (50 ug/mL)

    From: $61 Sizes: 2 mLCatalog #: 40048

    Propidium Iodide is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.

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    2 mL
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    Propidium Iodide is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.

     

    Propidium Iodide, 1 mg/mL in Water

    From: $42 Sizes: 10 mLCatalog #: 40017

    Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.

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    10 mL
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    Propidium iodide (PI) is a membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a cell population and also used as a counterstain in multicolor fluorescent imaging.