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Can GelRed™ and GelGreen™ be used to stain ssDNA or RNA?

GelRed™ and GelGreen™ can be used to stain both ssDNA and RNA, but GelRed is about 5 times more sensitive for single-stranded nucleic acids than GelGreen™. Titration assays using a fluorescence microplate reader showed that the fluorescence signal of GelRed™ bound to ssDNA and RNA is about half that of GelRed™ bound to dsDNA.

Category: GelRed™ and GelGreen™ Nucleic Acid Gel Stains

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