Nuclear Stains & DNA/RNA Dyes

Thiazole Red, also known as TO-PRO®-3, is a cell-impermeant, high-affinity far-red nucleic acid stain.

Thiazole red homodimer (TRhD), also known as TOTO®-3, is a cell-impermeant, high-affinity, far-red fluorogenic nucleic acid stain.

TO Iodide, also known as TO-PRO®-1, is a green fluorescent, cell-impermeant nucleic acid stain that can be used to stain dead or fixed cells.

Highly-selective dead cell stains for bacteria cultures. The stains are suitable for both gram-positive and gram-negative strains.

These kits include a BactoView™ Dead Stain and BactoView™ Viability Green Counterstain for two-color staining of live and dead bacteria. The kit is suitable for both gram-positive and gram-negative strains.

DAPI is a popular blue fluorescent DNA dye. The dye binds to the minor groove of dsDNA with approximately 20-fold fluorescence enhancement.

A high purity grade, red fluorescent nucleic acid dye for detecting nucleic acids in solution or for selectively staining dead cells with damaged plasma membranes.

Oxazole Blue, also known as PO-PRO™-1, is a blue-fluorescent, cell-impermeant nucleic acid stain that can be used to stain dead or fixed cells.

7-AAD (7-aminoactinomycin D) is a membrane-impermeant fluorescent DNA binding dye that is useful for live/dead discrimination and cell cycle profiling by flow cytometry.

Acridine orange (AO) stains dsDNA green (525 nm) and RNA or single stranded DNA red (650 nm). The dye is membrane-permeant and its nucleic acid binding property has been used for cell-cycle studies.

Actinomycin D is a nonfluorescent GC-selective intercalator. Similar to 7-AAD (cat. no. 40038), actinomycin D has also been used for chromosome banding studies.

Ethidium bromide (EtBr) is a widely used nucleic acid gel stain although it is also a known potent mutagen. EtBr is an intercalating DNA-binding dye with little sequence preference.

Hoechst dyes are cell membrane-permeant, minor groove-binding blue fluorescent DNA stains. Hoechst dyes are widely used in cell cycle and apoptosis studies as nuclear counterstains.

An improved alternative to 7-AAD showing less bleed-through fluorescence in the PE-Texas Red® channel. Ideal for selective detection of dead cells by flow cytometry.

A membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a mixed live-dead population and also used as a counterstain in multicolor fluorescent assays.