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Protease Substrates

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    Product

    D2R

    From: $148 Sizes: 2 mgCatalog #: 10210

    D2R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D2R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts.

     
    Product

    Ac-IETD-R110

    From: $354 Sizes: 5 mgCatalog #: 10207

    Z-IETD-R110 is a substrate for caspase-8, which is involved at the early stage of apoptosis, acting as an initiator of the caspase activation cascade.

     
    Product

    Dual Apoptosis Assay with NucView® 488 Caspase-3 Substrate & Annexin V

    From: $442 Sizes: 50 assaysCatalog #:
    30030
    , 30067, - 30073View allHide

    These kits provides two apoptosis markers, our novel NucView® 488 Caspase-3 Substrate and Annexin V conjugate for detecting caspase-3 activation and phosphatidylserine (PS) translocation.