Enzyme Substrates
Ac-IETD-R110
Z-IETD-R110 is a substrate for caspase-8, which is involved at the early stage of apoptosis, acting as an initiator of the caspase activation cascade.
BCIP Pink
A pink derivative of BCIP that produces a pink colored (λmax 540 nm) precipitate instead of the dark blue precipitate of BCIP. BCIP and derivatives are the most widely used chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins and are compatible with a variety of applications.
BCIP Pink/NBT Kit
NBT and BCIP PINK are widely used together as a chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins in a variety of applications, such as immunohistochemistry, westerns, and in situ hybridization. This kit contains 100 mg each of BCIP Pink (10006) and the precipitation inducer NBT (10008).
BCIP Red
A red derivative of BCIP that produces a red (λmax 565 nm) colored precipitate instead of the blue/violet precipitate of BCIP. BCIP and derivatives are the most widely used chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins and are compatible with a variety of applications.
BCIP Red/NBT Kit
A red derivative of BCIP that produces a red (λmax 565 nm) colored precipitate instead of the dark blue precipitate of BCIP. BCIP and derivatives are the most widely used chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins in a variety of applications.
BCIP, Na
10001, 10001-1, - 10001-2View allHide
A water soluble formulation of the most widely used chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins in a variety of applications, such as immunohistochemistry, westerns, and in situ hybridization.
BCIP, Toluidine
10002, 10002-1, - 10002-2View allHide
The most widely used chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins in a variety of applications, such as immunohistochemistry, westerns, and in situ hybridization. This form is soluble in DMF.
BCIP/NBT Kit
BCIP/NBT are widely used together as a chromogenic phosphatase substrate for the detection of alkaline phosphatase labeled proteins in a variety of applications, such as immunohistochemistry, westerns, and in situ hybridization. This kit contains 100 mg each of BCIP sodium salt (10001) and the oxidant NBT (Nitro blue tetrazolium, 10008).
BZAR
BZAR (Rhodamine 110, bis-(N-CBZ-L-arginine amide), dihydrochloride) is a substrate for serine proteases (1-5) and is also an inhibitor for quanidinobenzoatase. It is 50 to 100 times more sensitive than the AMC-based substrate.
BZiPAR
BZiPAR (Rhodamine 110, bis-(N-CBZ-L-isoleucyl-L-prolyl-L-arginine amide), dihydrochloride) is a substrate for trypsin (1,2). The substrate has been reported to enter live cells and be hydrolyzed by lysosomal proteases (3).
Chromogenic β-Galactosidase Substrate Sampler
For researchers wishing to investigate the suitability of our various chromogenic β-galactosidase substrates, we offer this sampler kit, which contains 5 mg each of the following five different substrates: X-Gal (10011), Red-β-D-Gal (10012), Rose-β-D-Gal (10013), Purple-β-D-Gal (10014) and Green-β-D-Gal (10015).
Chromogenic β-Glucuronidase Substrate Sampler
For researchers wishing to investigate the suitability of our various chromogenic β-glucuronidase substrates, we offer this sampler kit, which contains 5 mg each of the following three different substrates: X-GlcU, CHA, Red-β-D-GlcU, CHA, and Rose-β-D-GlcU, CHA.
Chromogenic Phosphatase Substrate Sampler
The sampler kit contains 10 mg each of BCIP Na (10001), BCIP Pink (10006), BCIP Red (10004) and 250 mg of NBT (10008). NBT forms a co-precipitant and enhances the BCIP reaction.
Coelenterazine
10123, 10126-50ug, 10126, 10110, 10110-2, 10110-1, 10127-50ug, 10127, 10111, 10111-2, 10111-1, 10112, 10112-2, 10112-1, 10113, 10113-2, 10113-1, 10114, 10114-2, 10114-1, 10115, 10115-2, 10115-1, 10116, 10116-2, 10116-1, 10117, 10117-2, 10117-1, 10124, 10124-2, 10121, 10121-2, 10121-1, 10125, 10125-2, 10125-1, 10122, - 10122-1View allHide
Coelenterazine and its analogs are luminescent enzyme substrates for apoaequorin and Renilla luciferase.
CTC (5-Cyano-2,3-ditolyl tetrazolium chloride)
5-Cyano-2,3-ditolyl tetrazolium chloride (CTC) has been used to evaluate the respiratory activity of many bacterial populations as well as populations undergoing drug efficacy evaluations. Healthy cells respiring via the electron transport chain will absorb and reduce CTC into an insoluble, red fluorescent formazan product.
D2R
D2R (Rhodamine 110, bis-(L-aspartic acid amide), ditrifluoroacetic acid salt) is a general substrate for caspases including caspases 3 and 7. Unlike other fluorogenic substrates for caspases, D2R appears to be membrane-permeant, and thus can be used to measure caspase activity in live cells without osmotic shock for flow cytometry studies, as well as for cell extracts.