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4-Bromo A-23187, Free Acid

Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2+ indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2+ to enter cells to quench indicator fluorescence.

Product Attributes

CAS number

76455-48-6

Applications

Ion indicator accessory reagents

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1 mg
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Product Description

Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2 indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2 to enter cells to quench indicator fluorescence. However, since 4-bromo A-23187 is nonfluorescent, it is preferred over the blue fluorescent A-23187 for calibrations of UV-excited Ca2 indicators such as Indo-1 and Fura-2 in order to keep background fluorescence to a minimum.

  • White solid soluble in DMSO or EtOH
  • Store at 4°C
  • C29H36BrN3O6
  • MW: 602.52
  • [76455-48-6]

 

References

1) Anal Chem 146, 349 (1985).

 

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