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Z-AAD-R110

Z-AAD-R110 is a substrate for granzyme B. Granzyme B from T lymphocytes and natural killer cells induces apoptosis in target cells by activating caspases and causing mitochondrial cytochrome C release.

Product Attributes

Excitation/Emission

496/520 nm (end product)

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Product Description

Z-AAD-R110 is a substrate for granzyme B. Granzyme B from T lymphocytes and natural killer cells induces apoptosis in target cells by activating caspases and causing mitochondrial cytochrome C release.

  • Ful name: Rhodamine 110, bis-(N-CBZ-L-alanyl-L-alanyl-L-aspartic acid amide)
  • λExEm of end product (R110) = 496/520 nm
  • Off-white to pink solid soluble in DMSO
  • Store at -20°C and protect from light
  • C56H56N8O17
  • MW: 1113.1

 

References

1. J Biol Chem 276, 6974 (2001).

 

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