Z-FR-R110 (Rhodamine 110, bis-(N-CBZ-L-phenylalanyl-L-arginine amide), dihydrochloride) is a substrate for the cysteine proteases cathepsins B and L. The substrate has been used in flow cytometry studies of human monocytes and rat macrophages.
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NucView® 488 Caspase-3 Enzyme Substrate, 1 mM in PBS
NucView® 488 Caspase-3 Substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3/7 activity within live cells in real time.
NucView® 405 Caspase-3 Substrate, 1 mM in DMSO
NucView® 405 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.
NucView® 530 Caspase-3 Substrate, 1 mM in DMSO
NucView® 530 Caspase-3 Substrate, 1 mM in DMSO, provides a convenient tool for detecting apoptosis in intact cells based on caspase-3/7 activity using either confocal microscopy or flow cytometry.
Dual Apoptosis Assay with NucView® 488 Caspase-3 Substrate & Annexin V
These kits provides two apoptosis markers, our novel NucView® 488 Caspase-3 Substrate and Annexin V conjugated with your choice of red or far-red dye. The kit is used for studying two important apoptosis events, caspase-3 activation and phosphatidylserine (PS) translocation.
Staurosporine is a potent and cell-permeable inhibitor of a wide variety of protein kinases (1,2) including protein kinase C (IC50 = 0.7 nM), protein kinase A (IC50 = 7 nM), and protein kinase G (IC50 = 8.5 nM). Staurosporine induces apoptosis in human neuroblastoma cells and chick embryonic neurons (3,4).