Cyanine 555 Tyramide
This Cyanine 555 tyramide conjugate is used for tyramide signal amplification (TSA)1,2,3, which is an enzyme-mediated detection method that uses horseradish peroxidase (HRP) to generate high-density labeling of a target protein or nucleic acid in situ.
Wishlist updated! View wishlist
Product Description
This Cyanine 555 tyramide conjugate is used for tyramide signal amplification (TSA)1,2,3, which is an enzyme-mediated detection method that uses horseradish peroxidase (HRP) to generate high-density labeling of a target protein or nucleic acid in situ. A tyramide conjugate is incubated in the presence of HRP (often bound to a secondary antibody), which catalyzes the binding of the tyramide (and associated label) to adjacent tyrosines for enhanced fluorescent signal. Cyanine 555 is structurally identical to Cy®3 from GE Healthcare.
Also see CF® Dye Tyramides, available with a wide selection of our bright and photostable CF® dyes.
Cy3 is a registered trademark of GE Healthcare.
References
1. Journal of Immunological Methods 125, 279-285 (1989).
2. Journal of Immunological Methods 137, 103-112 (1991).
3. Cytometry A. (2010), doi:10.1002/cyto.a.20970