Support & Resources

+1

TO Succinimidyl Ester

The amine reactive succinimidyl ester of TO (thiazole orange) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups.  The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in green fluorescence.

Size
Catalog #
price
Qty
5 mg
Clear selection
ADD TO CART
(Please select quantity above )

Wishlist updated! View wishlist

Protocols
SDS
Supporting Documents

Product Description

The amine reactive succinimidyl ester of TO (thiazole orange) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups.  The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in green fluorescence.  The conjugates might be useful for studies of nucleic acid binding to various biomolecules, such as DNA-binding proteins.  It is also possible that conjugates of other biomolecules might be capable of monitoring their transport into the nucleus.  TO dye conjugates of solid or semisolid matrices, such as microspheres, magnetic particles or various resins, might be useful for the detection or affinity isolation of nucleic acids.

  • λExEm (with DNA): 512/533 nm
  • Orange solid soluble in DMF or DMSO
  • C28H28N3O4S
  • Store at -20°C, desiccated and protected from light
  • MW: 503

 

 

See our other reactive DNA/RNA binding dyes.

 

You may also like…

    CF® Dye SE/TFP Ester

    CF® Dye SE/TFP esters are amine-reactive fluorescent dyes. They are commonly used to label primary amines of antibodies and other proteins, amine-modified oligonucleotides and other amine-containing molecules.

    EB Succinimidyl Ester

    The amine reactive succinimidyl ester of EB (ethidium bromide) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups.  The conjugates are expected to be essentially nonfluorescent until they are able to complex with nucleic acids, resulting in red fluorescence.

    MB Succinimidyl Ester

    The amine reactive succinimidyl ester of MB (methylene blue) can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups.  The conjugate will have a blue color and be able to complex with nucleic acids.

    EvaGreen® Dye, 20X in Water

    A patented green fluorescent nucleic acid dye with features that are ideal for applications such as qPCR, HRM®, LAMP, and digital PCR.

    GelRed® Nucleic Acid Gel Stain

    Ultra sensitive and environmentally safe replacement for EtBr DNA/RNA gel stain.

    GelGreen® Nucleic Acid Gel Stain

    GelGreen® is a sensitive, non-mutagenic and environmentally safer green fluorescent DNA gel stain.
40073