DNA/RNA Binding Dyes
Biotium has a wide selection of DNA-binding dyes for various applications. These include common classical dyes as well as novel dyes developed by Biotium.
Nuclear staining of cells in fluorescence microscopy: Biotium has developed novel nuclear stains such as Ethidium Homodimer III (EthD-III), RedDot™ dyes, and NucSpot® dyes. Click here for a complete listing of nuclear stains for fluorescence microscopy.
DNA dyes for gel staining: Biotium is the inventor of the two safest and most sensitive nucleic acid gel stains, GelRed® and GelGreen®.
Propidium Iodide (PI)
40016, 40017, - 40048View allHide
A membrane-impermeant nucleic acid intercalator. The dye is commonly used to selectively stain dead cells in a mixed live-dead population and also used as a counterstain in multicolor fluorescent assays.
Thiazole Green (SYBR® Green I), 10,000X in DMSO
40086-0.5mL, - 40086-1mLView allHide
Thiazole Green, which is structurally identical to SYBR® Green I Nucleic Acid Gel Stain, is one of the most sensitive stains available for detecting double-stranded DNA (dsDNA) in agarose, polyacrylamide gels and qPCR.
GelRed® Nucleic Acid Gel Stain
41001, 41002, 41003, 41002-1, 41003-1, - 41003-TView allHide
Ultra sensitive and environmentally safe replacement for EtBr DNA/RNA gel stain.
MB-Maleimide
A commonly used redox indicator in nucleic acid research. MB-Maleimide can be used to label molecules containing free thiol groups.
MB-Azide
A commonly used redox indicator in nucleic acid research. MB-Azide can be used to label alkyne, BCN, or phosphine-containing molecules.
MB-TCO
A commonly used redox indicator in nucleic acid research. MB-TCO (trans-cyclooctene) may be used to label tetrazine tagged molecules via a copper-free reaction.
MB-Methyltetrazine
A commonly used redox indicator in nucleic acid research. MB-methyltetrazine may be used to label TCO (trans-cyclooctene) tagged molecules via a copper-free reaction.
MB-DBCO
A commonly used redox indicator in nucleic acid research. MB-dibenzocyclooctyne (DBCO) allows copper-free bioorthogonal conjugation to spontaneously label molecules containing azide groups.
DAPI
40011, 40043, - 40009View allHide
DAPI is a popular blue fluorescent DNA dye. The dye binds to the minor groove of dsDNA with approximately 20-fold fluorescence enhancement.
PMA (Propidium Monoazide)
40013, - 40019View allHide
A photo-reactive DNA-binding dye typically used in viability PCR (v-PCR) of microorganisms like bacteria, viruses, and fungi.
Hoechst
40044, 40046, 40047, - 40045View allHide
Hoechst dyes are cell membrane-permeant, minor groove-binding blue fluorescent DNA stains. Hoechst dyes are widely used in cell cycle and apoptosis studies as nuclear counterstains.
GelRed® Prestain Plus 6X DNA Loading Dye
6X DNA loading buffer that includes ultra-sensitive, non-toxic GelRed® dye.
GelGreen® Agarose LE
41030-5G, - 41030-50GView allHide
Ultrapure molecular biology grade agarose pre-coated with GelGreen® Nucleic Acid Gel Stain for convenient and safer preparation of precast gels.
GelRed® Agarose LE
41029-5G, - 41029-50GView allHide
Ultrapure molecular biology grade agarose pre-coated with GelRed® Nucleic Acid Gel Stain for convenient and safer preparation of precast gels.
MB Acid
MB (methylene blue) acid can be conjugated to peptides, proteins, drugs, polymeric materials and biomolecules with primary amine groups. The conjugate will have a blue color and be able to complex with nucleic acids.
Thiazole Red Homodimer (TOTO®-3), 1 mM in DMSO
Thiazole red homodimer (TRhD), also known as TOTO®-3, is a cell-impermeant, high-affinity, far-red fluorogenic nucleic acid stain.