Thiol-Reactive Dyes

INA (5-iodonaphthyl-1-azide) is a lipophilic photoreactive probe, which has been used to selectively label membrane-embedded cysteine residues of proteins.

MTS-5-TAMRA (5-carboxytetramethylrhodamine methanethiosulfonate) is a fast-reacting and highly selective thiol-reactive label that permits one to attach the popular fluorescent dye TAMRA to a thiol group.

MTS-6-TAMRA (6-carboxytetramethylrhodamine methanethiosulfonate) is a fast-reacting and highly selective thiol-reactive label that permits one to attach the popular fluorescent dye TAMRA to a thiol group.

MTS-AMCA (7-amino-4-methylcoumarin-3-acetic acid methanethiosulfonate) readily labels a thiol with AMCA, a widely used UV-excitable, blue fluorescent dye.

2-((4-Azido-2,3,5,6-tetrafluorobenzoyl)amino)ethyl methanethiosulfonate is a cross-linker containing a thiol-reactive MTS group and a photoaffinity label 4-azido-2,3,5,6-tetrafluorobenzene (ATFB). ATFB is known to be a superior photoaffinity label that undergoes highly efficient C-H bond insertion on UV photolysis.

MTS-BCN is a fast-reacting and highly selective thiol-reactive label for attaching BCN to thiol groups on biomolecules. BCN, an alternative to DIBO and DBCO, reacts with azide to form 1,2,3-triazole by copper free 1,3-dipolar Huisgen cycloaddition.

MTS-CR110 (MTS-5-(and-6)-carboxyrhodamine 110, mixed isomers) is a green fluorescent thiol-reactive dye. CR110 (5-(and-6)-carboxyrhodamine 110) has absorption and emission spectra (502/524 nm) similar to those of fluorescein (495/519 nm) but its photostability is far better than that of the latter.

MTS-CR110-X (MTS-5-(and-6)-carboxyrhodamine 110-X, mixed isomers) is a green fluorescent thiol-reactive dye. It is similar to MTS-CR110 (catalog no. 91035) except that the former has a X spacer molecule between the dye and the MTS reactive group.

MTS-Rhodamine 6G is a fast-reacting and highly selective thiol-reactive rhodamine dye.

MTS-ROX (MTS-5(6)-carboxy-X-rhodamine) is a fast-reacting and highly selective thiol-reactive rhodamine dye.

MTS-sulforhodamine 101 is a fast-reacting and highly selective thiol-reactive rhodamine dye.

MTS-TAMRA (MTS-5(6)-carboxytetramethylrhodamine, mixed isomers) is a fast-reacting and highly selective thiol-reactive label that permits one to attach the popular fluorescent dye carboxytetramethylrhodamine to a thiol group.

MTSBS (4-Sulfonatobutyl methanethiosulfonate sodium salt) is a negatively charged MTS reagent.

MTSEA (2-Aminoethyl methanethiosulfonate hydrobromide) is a positively charged MTS reagent.

MTSEH (2-Hydroxyethyl methanethiosulfonate) is a neutral MTS reagent.

MTSES (2-Sulfonatoethyl methanethiosulfonate sodium salt) is a negatively charged MTS reagent.