Reagents for Nitric Oxide (NO) & Reactive Oxygen Species (ROS)

A potent and moderately selective inhibitor of inducible nitric oxide synthase (iNOS) over other NOS isoforms.

A chemical solution that is used for absorbance-based nitrite detection in biological samples such as cell lysates or tissue perfusates.

H₂DCFDA (2′,7′-Dichlorodihydrofluorescein diacetate) is a useful fluorogenic reagent to detect reactive oxygen intermediates in cells. On oxidation, H₂DCFDA becomes the highly green fluorescent 2′,7′-dichlorofluorescein.

A collection of popular inhibitors of the nitric oxide synthase isoforms, commonly used for studies of the biochemical and physiological functions of NO.

A probe for nitric oxide (NO) that forms a red (λ _Em 580 nm) fluorescent precipitate after reacting with NO.

A non-selective, potent, and irreversible inhibitor of nitric oxide synthase isoforms.

A competitive inhibitor of nitric oxide synthase in a wide range of cells.

A selective inhibitor for nitric oxide synthase (NOS) in brain tissues.

Releases nitric oxide by spontaneously dissociating in a pH-dependent manner and is useful for reliable and controllable NO generation in solution.

Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and induce cGMP production.

Dihydroethidium (also called hydroethidium) is the chemically reduced form of the commonly used DNA dye ethidium bromide. The probe is useful to detect oxidative activities in viable cells, including respiratory burst in phagocytes.

Dihydrorhodamine 123 is the reduced form of rhodamine 123 (70010), which is a commonly used fluorescent mitochondrial dye.

Dihydrorhodamine 123 dihydrochloride is functionally equivalent to dihydrorhodamine 123 (10055) but with increased stability toward air oxidation and light during storage.

2,3 Diaminonaphthalene is a fluorometric probe for nitrite. It reacts  to form the fluorescent dye 1 H-naphthotriazole.

Releases nitric oxide spontaneously under physiological conditions and plays an essential role in the biochemical and physiological functions of nitric oxide pathways.

Generate nitric oxide and form superoxides spontaneously under physiological conditions and is often used to probe the cell stress response and stimulate calcium-independent synaptic vesicle release.