Biotin & Streptavidin Conjugates

Biotin BCN, an alternative to biotin labeled DIBO and DBCO, reacts with azide to form 1,2,3-triazole by copper free 1,3-dipolar Huisgen cycloaddition.

Biotin-PEO₄-maleimide is a water soluble biotin derivative that can be readily coupled to thiols.

Biotin-PEO₄-hydrazide is a water-soluble biotin derivative capable of reacting with aldehydes or ketones to form hydrazones.

Biotin-12 SE is an amine-reactive biotin derivative with a long spacer group. It is useful for making biotin labeled nucleoside triphosphates among other applications.

Biotin-X cadaverine (5-(((N-(Biotinoyl)amino)hexanoyl)amino) pentylamine, free base) can be coupled directly to activated carboxylic acid esters without the use of a base.

Biotin-PEO₂-PPO₂-amine trifluoroacetic acid (TFA) salt is a water soluble biotin derivative with an amine group.

Biotin cadaverine free base (N-(5-Aminopentyl)biotinamide) can be directly coupled to activated carboxylic acid groups without using an additional base.

Biotin ethylenediamine, hydrochloride is functionally equivalent to Neurobiotin™ (biotin ethylenediamine, hydrobromide, 90057).

Biotin ethylenediamine in free base form. White solid soluble in DMSO.

Biotin-PEO₄-amine is a water soluble biotin derivative that can be readily coupled to activated carboxylic acids.

Biotin-PEO₄-propionate SE (Biotin-PEO₄-propionate succinimidyl ester) is a water soluble biotin derivative that can be readily coupled to primary or secondary amines.

Biotin cadaverine, biotin-X cadaverine (90061), and biotin ethylenediamine (90057) can be coupled to carboxylic acids, DNA and other biomolecules.

Biotin-PEO₃-amine is a water soluble biotin derivative that can be readily coupled to activated carboxylic acids.

Biotin-4-fluorescein (N-(5-aminopentyl)biotinamide, trifluoroacetic acid salt) has been reported to be a superior fluorescent biotin derivative for accurate measurement of avidin and streptavidin in crude biological samples. Binding of biotin to avidin and streptavidin is high affinity, fast and noncooperative.

Biotin-X cadaverine trifluoroacetic acid salt (5-(((N-(biotinoyl)amino)hexanoyl)amino) pentylamine, trifluoroacetic acid salt) can be coupled to activated carboxylic acid esters or sulfonyl chlorides in the presence of a base or in a basic buffer. Also see biotin-X cadaverine free base (90080).

Biotin-X-C₅-maleimide (N-(biotinoyl)-N’-(iodoacetyl)ethylenediamine) is readily and selectively coupled to thiols.