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Coelenterazine e

Coelenterazine e is a synthetic derivative of coelenterazine, and is a superior substrate for Renilla luciferase.  Coelenterazine e generates nearly 40% more light than native coelenterazine does while the initial light intensity of the former is more than 7 times higher than that of the latter

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CAS number

114496-02-5

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Product Description

Coelenterazine e is a synthetic derivative of coelenterazine, and is a superior substrate for Renilla luciferase.  Coelenterazine e generates nearly 40% more light than native coelenterazine does while the initial light intensity of the former is more than 7 times higher than that of the latter.  The emission spectrum of coelenterazine e/Renilla luciferase has two peaks centered at 418 and 475 nm, respectively.Coelenterazine e is also a good substrate for apoaequorin and, compared with coelenterazine native, the e-aequorin compelx formed from coelenterazine e has a faster luminescence rise time and shows two emission peaks at 405 and 465 nm respectively, with the ratio of the peak heights dependent on calcium concentration in the range pCa 5-7.  The dual emission makes coelenterazine e/apoaequorin possible to be used for calcium detection using the ratio of the two emission intensities.

  • Yellow solid soluble in MeOH or EtOH
  • Store at -20°C and protect from light
  • C28H23N3O3
  • MW: 449.50

 

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