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What is the mechanism of RedDot™ 1 or RedDot™ 2 binding to DNA? Are the dyes intercalators, or minor groove binders?

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The mechanism of binding for RedDot™ 1 and RedDot™ 2 to DNA has not been characterized. However, based on the dye structure, it may bind by a similar mechanism as DRAQ®5, which has been reported in the literature to be a concentration-dependent intercalator and minor groove binder.

DRAQ is a registered trademark of Biostatus, Ltd.

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