Monoclonal anti TAG 72 / CA72.4 (CA72/145)

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Catalog #: BNUB0145
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Product Description

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.

Lottich SC et. al. Breast Cancer Research and Treatment, 1985, 6(1):49-56. | Thor A et. al. Cancer Research, 1986, 46(6):3118-24

Additional Information

Conjugation

Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP

Size

50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type

Primary

Host species

Mouse

Reactivity (target)

TAG-72 / CA72.4 (CA72/145)

Clonality

Monoclonal

Clone

CA72/145

Isotype

IgG1, kappa

Molecular weight

220 kDa

Synonyms

CA72.4, Tumor associated glycoprotein 72

Entrez gene ID

182875

SwissProt

Not Known

Immunogen

Human CA72.4 protein

Unigene

Not Known

Species reactivity

Human

Applications

Immunoprecipitation, Flow cytometry, Immunofluorescence, Western

Cellular localization

Cytoplasmic and cell surface

Application notes

Flow Cytometry (0.5-1 ug/million cells/0.1 mL), Immunofluorescence 1-2 ug/mL, Immunoprecipitation 1-2 ug/500 ug protein lysate, Optimal dilution for a specific application should be determined by user, Western blotting 0.5-1 ug/mL

Positive control

Jurkat cells, Breast or lung carcinoma.

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

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