Support

Quick links
Frequently asked questions - categories
Ask a question
Contact Us
+1

NOS Inhibitor Kit

This kit contains four nitric oxide synthase (NOS) inhibitors: 7-NI (00240) (50 mg), L-NMMA (00241) (25 mg), L-NIL (00242) (5 mg) and L-NIO (00243) (5 mg).

Product Attributes

Storage Conditions

See individual components for storage temperature, Desiccate

CAS number

2942-42-9, 53308-83-1, 150403-89-7, 36889-13-1

Size
Catalog #
price
Qty
1 kit
Clear selection
Add to wishlist
ADD TO CART
(Please select quantity above )

Wishlist updated! View wishlist

Shipping, Handling & Tax (CA only) not included in price. Learn more

Tax is assessed in the state of California. All fees will be calculated during checkout based on your shipping information and are subject to change.

SPECIAL - Order 5 or more and receive 10% off.

Request a Bulk Quote

Product Description

This kit contains four nitric oxide synthase (NOS) inhibitors: 7-NI (00240) (50 mg), L-NMMA (00241) (25 mg), L-NIL (00242) (5 mg) and L-NIO (00243) (5 mg).

7-NI is a selective inhibitor for the brain nitric oxide synthase (NOS).

  • Yellow orange solid soluble in DMSO
  • Store desiccated at 4°C
  • C7H5N3O2
  • MW: 163.1
  • [2942-42-9]

L-NMMA (NG-Methyl-L-arginine, acetate salt) competitively inhibits nitric oxide synthase in a wide range of cells.

  • White solid soluble in water
  • Store desiccated at 4°C
  • C9H20N4O4
  • MW: 248.3
  • [53308-83-1]

L-NIL (N6-(1-Iminoethyl)-lysine, hydrochloride) is a potent and selective inhibitor of nitric oxide synthase that exhibits about 28-fold greater selectivity for inducible nitric oxide synthase (IC50 = 3.3 uM) than for the rat brain constitutive enzyme (IC50 = 92 uM). It exhibits about 10-fold greater inhibitory potency than NG-monomethyl-L-arginine in inhibiting γ-interferon-induced NO2– production (IC50 = 460 nM).

  • White solid soluble in water
  • Store at 4°C
  • C8H19Cl2N3O2
  • MW: 260.2
  • [150403-89-7]

L-NIO (N5-(1-Iminoethyl)-L-ornithine, dihydrochloride) is a potent, irreversible inhibitor of neutrophil nitric oxide synthase.

  • White solid soluble in water
  • Store desiccated at -20°C
  • C7H17Cl2N3O2
  • MW: 246.1
  • [36889-13-1]

References

n/a

 

You may also like…

    Griess Reagent Kit

    Griess reagent is used to detect nitrite photometrically. The kit includes ready-to-use Griess reagent, nitrite standard solution, and a detailed protocol.

    DAA

    DAA (1,2-Diaminoanthraquinone) reacts with nitric oxide (NO) to form a red (λ Em 580 nm) fluorescent precipitate. DAA has been used to detect NO concentration in rat retinas after injury to the optic nerve.

    SNAP

    SNAP (S-Nitroso-N-acetylpenicillamine) releases nitric oxide under physiological conditions and also been shown to be a potent vasodilator.

    DEA-NONOate

    DEA-NONOate (2-(N,N-Diethylamino)-diazenolate-2-oxide, diethylammonium salt) releases nitric oxide spontaneously under physiological conditions. Useful for reliable NO generation in solution.

    Dihydroethidium (Hydroethidium)

    Dihydroethidium (also called hydroethidium) is the chemically reduced form of the commonly used DNA dye ethidium bromide. The probe is useful to detect oxidative activities in viable cells, including respiratory burst in phagocytes.

    Dihydrorhodamine 123

    Dihydrorhodamine 123 is the reduced form of rhodamine 123 (70010), which is a commonly used fluorescent mitochondrial dye.