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7-Nitroindazole (7-NI)

A selective inhibitor for nitric oxide synthase (NOS) in brain tissues.

Product Attributes

CAS number

2942-42-9

Molecular weight

163.1

Storage Conditions

Store at 2 to 8 °C, Desiccate

Molecular Formula: C7H5N3O2

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50 mg
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Product Description

7-Nitroindazole (7-NI) is a selective inhibitor for the brain nitric oxide synthase (NOS) and is often used to study of nitric oxide (NO) activity in the brain.

  • Selective inhibition of nitric oxide synthase in brain tissues
  • Yellow orange solid soluble in DMSO

If a variety of NOS inhibitors are needed, we offer a NOS Inhibitor Kit which contains four four NOS inhibitors: 7-NI (00240) (50 mg), L-NMMA (00241) (25 mg), L-NIL (00242) (5 mg) and L-NIO (00243) (5 mg). We also have a selection of dyes and probes for detecting nitric oxide or reactive oxygen in cells.

Molecular Structure:

References

  1. Meth in Enzymol 268, 393 (1995), DOI: 10.1016/S0076-6879(96)68041-0
  2. Stroke 26, 2172 (1995), DOI: 10.1161/01.STR.26.11.2172
  3. Br J Pharmacol 110, 225 (1993), DOI: 10.1111/j.1476-5381.1993.tb13796.x
 

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