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TMR Biocytin

TMR biocytin is a cell-impermeant, fixable polar tracer that combines the tetramethylrhodamine (TAMRA) with biotin and an aldehyde-fixable primary amine.  Polar tracers are commonly used to investigate cell-cell and cell-liposome fusion as well as membrane permeability and transport through gap junctions or cell uptake during pinocytosis.

Product Attributes

Cellular localization

Fluid phase tracer

Cell permeability

Membrane impermeant

Colors

Red

Excitation/Emission

544/571 nm

Conjugation

Biotin, Tetramethylrhodamine (TRITC)

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5 mg
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Product Description

TMR biocytin is a cell-impermeant, fixable polar tracer that combines the tetramethylrhodamine (TAMRA) with biotin and an aldehyde-fixable primary amine.  Polar tracers are commonly used to investigate cell-cell and cell-liposome fusion as well as membrane permeability and transport through gap junctions or cell uptake during pinocytosis. TMR biocytin has proved to be an effective neuronal tracer in live tissue when applied by electroporation1.

  • λExEm: 544/571 nm
  • Dark red solid soluble in DMF or DMSO
  • MW: 871

We also offer CF® Dye-Biocytin, with a selection of our superior CF® dyes.

References

1. Journal of Neuroscience Methods (2015), http://dx.doi.org/doi:10.1016/j.jneumeth.2015.06.005

 

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