Support & Resources

+1

Transferrin (human) CF® Dye Conjugates

Labeled human transferrin is used for microscopic studies of the endosomal pathway and/or transferrin uptake studies.

Product Attributes

Cellular localization

Membrane/vesicular

For live or fixed cells

For live/intact cells

Assay type/options

Real-time imaging

Cell permeability

Membrane impermeant

Fixation options

Fix after staining (formaldehyde), Permeabilize after staining, Fix before staining (formaldehyde)

Colors

Green, Orange, Red, Far-red, Near-infrared

Conjugation
Don’t see what you’re looking for? Contact us for more conjugation options.
Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
Size
Catalog #
price
Qty
1 mg
Clear selection
Add to wishlist
ADD TO CART
(Please select quantity above )

Wishlist updated! View wishlist

Shipping, Handling & Tax (CA only) not included in price. Learn more

Tax is assessed in the state of California. All fees will be calculated during checkout based on your shipping information and are subject to change.

SPECIAL - Order 5 or more and receive 10% off.

Request a Bulk Quote

Product Description

Labeled human holo-transferrin is used for microscopic studies of the endosomal pathway and/or transferrin uptake. Biotium’s holo-transferrin conjugates are labeled with a selection our CF™ dyes, a series of next-generation fluorescent dyes developed at Biotium to have combined advantages in brightness, photostability, and water solubility compared to other fluorescent dyes.

  • Choice of 7 CF® dyes from green to near-infrared
  • Superior CF® dyes are bright, photostable, and water-soluble
  • For endocytosis and transferrin uptake studies

Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron-binding domains that binds up to two Fe(III) atoms for delivery to vertebrate cells through receptor-mediated endocytosis. After binding to its receptor on the cell surface, transferrin is rapidly internalized by invagination of clathrin-coated pits with formation of endocytic vesicles, the acidic environment favors dissociation of iron from the transferrin-receptor complex. Following the release of iron, the transferrin is then recycled back to the surface of the cell via the endocytic recycling pathway and released to bind more iron.

Superior CF® Dyes

Biotium’s next-generation CF® dyes were designed to be highly water-soluble with advantages in brightness and photostability compared to Alexa Fluor®, DyLight®, and other fluorescent dyes. Learn more about CF® Dyes.

CF® Dye Human Transferrin

ProductEx/EmSizeCatalog No.
CF®488A Human Transferrin490/515 nm1 mgPurchase 00081
CF®543 Human Transferrin541/560 nm1 mgPurchase 00082
CF®568 Human Transferrin562/583 nm1 mgPurchase 00083
CF®594 Human Transferrin593/614 nm1 mgPurchase 00084
CF®640R Human Transferrin642/662 nm1 mgPurchase 00085
CF®680R Human Transferrin663/682 nm1 mgPurchase 00086
CF®750 Human Transferrin755/777 nm1 mgPurchase 00087

 

CF is a registered trademark of Biotium, Inc. Alexa Fluor, Texas Red, and DyLight are registered trademarks of Thermo Fisher Scientific.

References

Download a list of CF® dye references.

 

You may also like…