Cytosolic Tracers
5-Carboxy-2′,7′-dichlorofluorescein (single isomer)
This dye can be used as a low pH indicator similar to 51015, and is also useful as a general green fluorescent label.
5-(and-6)-Carboxy-2′,7′- dichlorofluorescein
5-(and-6)-carboxy-2′,7′-dichlorofluorescein is similar to carboxyfluorescein (51013), but has lower pKa. It is useful for detecting pH in more acidic environment.
CDCFDA
5-(and-6)-Carboxy-2′,7′-dichlorofluorescein diacetate is membrane-permeant and thus can be loaded into cells via incubation. The diacetate is readily hydrolyzed to 5-(and-6)-carboxy-2′,7′-dichlorofluorescein (51015) by intracellular esterases.
5-(and-6)-Carboxyfluorescein
5-(and-6)-FAM (full name: 5-(and-6)-Carboxyfluorescein mixed isomer) has a pKa of 6.5 and can be used as a pH indicator.
Biotin-cGMP, Diisopropylethylammonium Salt
00021, - 00021-1View allHide
A biotinylated cyclic nucleotide that is an important second messenger in many biological processes and has been used as a tracer in immunoassays.
Biotin-cAMP
00020, - 00020-1View allHide
A biotin-conjugated cAMP analog that can be used to probe cAMP receptors.
Calcein AM
80011, 80011-1, 80011-2, - 80011-3View allHide
Calcein AM is a widely used green fluorescent cell marker. Calcein AM is membrane-permeant and thus can be introduced into cells via incubation.
CF® Dye Hydrazide
96063, 96064, 92136, 92151, 92152, 92153, 92154, 92156, 92157, 92158, 92183, 96024, - 96025View allHide
Fluorescent CF® dye hydrazides are bright, extremely water-soluble, nontoxic molecules, useful as aldehyde-fixable cell tracers. They can also be used to label aldehyde or ketone groups of polysaccharides, carbohydrates or glycoproteins.
CF® Dye Biocytin
92004, 92005, 92006, - 92007View allHide
CF® Dye biocytin is a cell-impermeant, fixable polar tracer that is a conjugate of CF® Dye and biotin with an aldehyde-fixable primary amine. Polar tracers are commonly used to investigate cell-cell and cell-liposome fusion as well as membrane permeability and transport through gap junctions or cell uptake during pinocytosis.
CF®DI Hydrazide
92164, 92165, 92166, 92184, - 92185View allHide
CF®DI dye hydrazides react with carbonyl moieties of aldehyde or ketone groups. They are size- and charge-matched for detection of protein carbonylation by fluorescence two-dimensional differential gel electrophoresis (2D-DIGE).
CF® Dye Dextran 10,000 MW, Anionic and Fixable
80110, 80111, 80112, 80113, 80114, 80115, 80116, 80118, 80119, 80120, - 80121View allHide
CF® Dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 10,000 MW, and contains a formaldehyde-fixable free-amine group.
Bovine Serum Albumin CF® Dye Conjugates
20289, 20290, 20291, - 20292View allHide
Bright and photostable fluorescent BSA conjugates for applications in which well-defined molecular weight fluid phase tracers are needed. These applications include studying the rate of endocytosis and exocytosis and following vesicle trafficking.
CF® Dye Dextran 3,500 MW, Anionic and Fixable
CF® Dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 3,500 MW, and contains a formaldehyde-fixable free-amine group.