Neuroscience

SynaptoGreen™ C5 is similar to SynaptoGreen™ C4 (70020), except that the lipophilic tail is one carbon longer.

SynaptoRed™ C1 is similar to the widely used red fluorescent nerve terminal dye SynaptoRed™ C2 (also called FM®4-64) except that the lipophilic tail of SynaptoRed™ C1 is one carbon shorter than that of the SynaptoRed™ C2.

A widely used red fluorescent dye for following synaptic activity by staining synaptic vesicles at the synapse or neuromuscular junctions. When used in combination with the green fluorescent dye SynaptoGreen™ (70020), synapses or neuromuscular junctions can be imaged independently in two colors. SynaptoRed™ has also been used to study endocytosis in Dictyostelia.

SynaptoRed™ C2M is a red fluorescent probe used to follow synaptic vesicles.

DSL binds to (beta-1,4) linked N-acetylglucosamine oligomers, preferring chitobiose or chitotriose over single N-acetylglucosamine residues. Biotium offers DSL conjugated to biotin and a selection of 6 bright and photostable CF® Dyes.

Tomato lectin (LEL, TL) CF® Dye conjugates that bind to [GlcNAc] 1,3-N-acetylglucosamine, glycophorin, and Tamm-Horsfall glycoprotein. LEL, TL is a commonly used marker for blood vessels and microglial cells in rodent and neuroscience research. Biotium offers tomato lectin conjugated to biotin and a selection of 6 bright and photostable CF® Dyes.

PHA-L triggers lymphocyte agglutination and is available conjugated to biotin and a selection of 6 bright and photostable CF® Dyes.

UEA I binds to glycoproteins and glycolipids containing α-linked fucose residues, such as ABO blood group glycoconjugates. The lectin is an established marker for human endothelial cells and has been used to differentiate between angiosarcomas and epithelial tumors. Biotium offers UEA I conjugated to biotin and a selection of 6 bright and photostable CF® Dyes.

A wheat germ agglutinin (WGA) lectin labeled with Biotium’s CF® Dyes, biotin, or HRP. It is a carbohydrate-binding lectin that has high affinity for sialic acid and N-acetylglucosamine and stains yeast bud scars as well as the cell membrane of gram+ bacteria and mammalian cells.

A high affinity inhibitor of the nicotinic acetylcholine receptor in the neuromuscular junction. Blocks acetylcholine activity at the postsynaptic membrane.

ADVASEP-7 is a sulfonated β-cyclodextrin derivative that has been reported to reduce background fluorescence when using SynaptoGreen C4 (also called FM1-43, catalog no. 70020) to stain brain slices.

AM1-43 (equivalent to FM®1-43FX) is a fixable, activity-dependent fluorescent nerve terminal probe. AM1-43 functions similarly similarly to SynaptoGreen C4 (catalog # 70020), but with the additional property of being fixable.

AM1-44 is a version of AM1-43 (catalog no. 70024) with improved fixability. The dye can also be used as a general probe for following endocytosis.

AM2-10 is a fixable analog of SynaptoGreen™ C2.

AM3-25 is a lipophilic styryl dye that has an amine group at the hydrophilic head. The amine group reacts with formaldehyde or glutaldehyde to make the dye fixable.

AM4-64 is a fixable, activity-dependent fluorescent nerve terminal probe. AM4-64 functions similarly similarly as SynaptoRed™ C2 (#70021) (equivalent to FM®4-64), but with the additional property of being fixable.