Monoclonal anti Retinol Binding Protein 1 (RBP/872)

BNUB0872-0
BNUB0872-1
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Catalog #: BNUB0872
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Product Description

Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.

Naylor, H.M., et al. 1999. The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy-terminus of RBP. Biochemistry 38: 2647-2653

Additional Information

Conjugation

Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP

Size

50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type

Primary

Host species

Mouse

Reactivity (target)

Retinol Binding Protein-1 (RBP1/872)

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone

RBP/872

Molecular weight

21-25 kDa

Synonyms
Entrez gene ID

5947, 5948 & 5950

SwissProt

P02753, P09455 & P50120

Immunogen

Recombinant human retinol binding protein-1 (RBP1)

Unigene

529571

Species reactivity

Goat, Human, Monkey, Mouse, Rabbit, Rat

Applications

Immunofluorescence, Immunohistology (formalin)

Cellular localization

Cytoplasmic

Application notes

Immunofluorescence 1-2 ug/mL, Immunohistology formalin-fixed 1-2 ug/mL for 30 minutes at RT, Optimal dilution for a specific application should be determined by user, Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Positive control

Hepatic or ovarian carcinoma

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

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