Support & Resources

+1

MTS-BCN

MTS-BCN is a fast-reacting and highly selective thiol-reactive label for attaching BCN to thiol groups on biomolecules. BCN, an alternative to DIBO and DBCO, reacts with azide to form 1,2,3-triazole by copper free 1,3-dipolar Huisgen cycloaddition.

Product Attributes

Chemical reactivity (reacts with)

Azides/Picolyl azides, Thiols

Functional group

BCN, MTS

Storage Conditions

Store at -10 to -35 °C

Learn more about

Size
Catalog #
price
Qty
1 mg
Clear selection
Add to wishlist
ADD TO CART
(Please select quantity above )

Wishlist updated! View wishlist

Shipping, Handling & Tax (CA only) not included in price. Learn more

Tax is assessed in the state of California. All fees will be calculated during checkout based on your shipping information and are subject to change.

SPECIAL - Order 5 or more and receive 10% off.

Request a Bulk Quote

Product Description

BCN (bicyclo[6.1.0]nonyne) with an MTS (methanethiosulfonate) reactive group is a fast-reacting, highly selective thiol-reactive label that can be used to attach BCN moieties to thiol groups on target molecules. BCN, an alternative to DIBO and DBCO, reacts with azide to form 1,2,3-triazole by copper-free 1,3-dipolar Huisgen cycloaddition.   This copper-free bioorthogonal reaction allows staining the surface of live cells or in cell extracts when there are concerns about native protein function loss with copper.

  • Thiol-reactive BCN derivative.
  • BCN, an alternate to DIBO and DBCO, reacts with azide groups via copper-free bioorthogonal reaction.
  • Supports copper-free bioorthogonal reaction for labeling the surface of live cells or in cell extracts.

 

 

You may also like…

    CF® Dye Azide

    CF® dyes with an azide group. Can be used to label or detect alkyne, BCN or cyclooctyne-containing molecules by fluorescence spectroscopy, microscopy or flow cytometry following copper-catalyzed azide-alkyne cycloaddition.

    CF® Dye Maleimides

    CF® Dye Maleimides are thiol-reactive fluorescent dyes. Maleimides are commonly used to label proteins, peptides or other molecules containing free thiol groups.

    CPM

    CPM is a widely used blue fluorescent thiol-reactive dye that is essentially nonfluorescent until it reacts with thiols, making it possible to quantify thiols without a separation step.

    Biotin TS Ethylenediamine

    TS biotin ethylenediamine (Biotin ethylenediamine thiosulfate, sodium salt) is a highly selective thiol labeling probe. Similar to the MTS group, TS (thiosulfate) group is capable of reacting with thiols at nearly neutral pH.

    DMSO, Anhydrous

    Anhydrous DMSO (dimethyl sulfoxide; methyl sulfoxide) is recommended for preparing stock solutions of AM ester dyes, reactive dyes and other related moisture-sensitive products.

    CF® Dye Picolyl Azide

    CF® dye picolyl azide derivatives fluorescently label alkyne groups on biomolecules via the standard azide-alkyne cycloaddition, but at low copper concentrations.