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α-Bungarotoxin

A high affinity inhibitor of the nicotinic acetylcholine receptor in the neuromuscular junction. Blocks acetylcholine activity at the postsynaptic membrane.

Product Attributes

Toxin

Alpha-bungarotoxin

CAS number

11032-79-4

Molecular weight

7984

For live or fixed cells

For fixed cells, For live/intact cells

Cell permeability

Membrane impermeant

Storage Conditions

Store at -10 to -35 °C, Protect from light

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Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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Product Description

A potent neurotoxin that is an inhibitor for the motor endplate acetylcholine receptor (Kd = 1 nM to 1 pM). It binds at the neuromuscular junction with high affinity and is often used to study neuromuscular junctions by blocking cholinergic receptors. The toxin also blocks α7 receptors, located in the central and peripheral nervous systems.

  • A polypeptide snake toxin
  • Blocks and inhibits cholinergic receptors
  • White solid soluble in water

Also see our Fluorescent α-Bungarotoxins and Biotin α-Bungarotoxin which can can be used for labeling of nicotinic acetylcholine receptors at neuromuscular junctions in tissue sections. See our complete selection of α-Bungarotoxins below.

α-Bungarotoxin, CF® Dye and Other Conjugates

ConjugationEx/EmSizeCatalog No.Dye Features
UnconjugatedN/A1 mg00010-1
Biotin-XXN/A0.5 mg00017
CF®405S404/431 nm100 ug00002-100ugCF®405S Features
0.5 mg00002
CF®488A490/515 nm100 ug00005-100ugCF®488A Features
0.5 mg00005
CF®543 541/560 nm100 ug00026-100ugCF®543 Features
0.5 mg00026
CF®555555/565 nm100 ug00018-100ugCF®555 Features
0.5 mg00018
CF®568562/583 nm100 ug00006-100ugCF®568 Features
0.5 mg00006
CF®594596/614 nm100 ug00007-100ugCF®594 Features
0.5 mg00007
CF®633630/650 nm100 ug00009-100ugCF®633 Features
0.5 mg00009
CF®640R642/662 nm100 ug00004-100ugCF®640R Features
0.5 mg00004
CF®680R680/701 nm100 ug00003-100ugCF®680R Features
0.5 mg00003
Fluorescein
(FITC)
494/518 nm0.5 mg00011
10 x 50 ug00013
Tetramethylrhodamine
(TRITC)
553/577 nm0.5 mg00012
10 x 50 ug00014
Sulforhodamine-101
(Texas Red®)
593/613 nm0.5 mg00015
10 x 50 ug00016

 

CF is a registered trademark of Biotium, Inc. Texas Red is a registered trademark of Thermo Fisher Scientific.
 

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