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CD4 Monoclonal Mouse Antibody (SK3) – Biotium Choice

CD4 (clone SK3) is a validated mouse monoclonal antibody that recognizes CD4, a membrane glycoprotein of T lymphocytes. The antibody belongs to the Biotium Choice list of select antibodies that have been validated and optimized in-house for optimal performance.

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Product Description

CD4 (clone SK3) is a mouse monoclonal antibody that recognizes the extracellular domain of CD4, a membrane glycoprotein of T lymphocytes. This antibody belongs to the Biotium Choice list of select antibodies that have been validated and optimized in-house for optimal performance. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.

CD4 interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4/CD8. Anti-CD4 is used in the immunohistochemical staining of lymphoproliferative disorders to evaluate tumors with CD4 aberrant expression.

As an isotype control, we recommend Isotype Control, Monoclonal Mouse IgG1 Kappa (IGG1/1331) for this antibody.

Discover Sharper Signals and Unmatched Panel Flexibility with Biotium Choice Antibodies
Powered by CF® Dyes and Astral Leap™ Tandem Dyes

Biotium Choice antibodies are carefully curated and validated in-house to offer exceptional signal-to-noise. Labeled with our advanced CF® Dyes and Astral Leap™ tandem dyes, they are our top-recommended antibodies for flow cytometry and other applications.

Biotium Choice Antibody Features

  • Robust and validated clones against common targets
  • Developed and optimized for flow cytometry and other applications
  • Conjugated to bright, photostable CF® Dyes for superior signal and clarity
  •  Also available with Astral Leap™ tandem dyes for expanding multiplexing
  • New antibody clones and dye conjugates continuously in development

View our full catalog of Biotium Choice antibodies

Identifying Biotium validated antibodies

Biotium scientists validate and optimize select antibodies in our catalog, marked with a check mark next to the product name. This symbol indicates the antibody is highly recommended for the specified application(s).

Look for this symbol next to the product name on product pages and search results

CD4 Monoclonal Mouse Antibody (SK3) - Biotium Choice

ConjugationEx/EmConc.SizeCatalog No.Dye Features
CF®405S411/431 nm100 ug/mL25 tests (125 uL)P001-405S-125CF®405S Features
100 tests (500 uL)P001-405S-500
CF®405M416/452 nm100 ug/mL25 tests (125 uL)P001-405M-125CF®405M Features
100 tests (500 uL)P001-405M-500
CF®405L413/547 nm200 ug/mL25 tests (125 uL)P001-405L-125CF®405L Features
100 tests (500 uL)P001-405L-500
CF®488A490/516 nm100 ug/mL25 tests (125 uL)P001-488A-125CF®488A Features
100 tests (500 uL)P001-488A-500
CF®503R503/532 nm50 ug/mL25 tests (125 uL)P001-503R-125CF®503R Features
100 tests (500 uL)P001-503R-500
CF®514516/549 nm100 ug/mL25 tests (125 uL)P001-514-125CF®514 Features
100 tests (500 uL)P001-514-500
CF® 568562/584 nm50 ug/mL25 tests (125 uL)P001-568-125CF®568 Features
100 tests (500 uL)P001-568-500
CF® 575575/601 nm25 ug/mL25 tests (125 uL)P001-575-125
100 tests (500 uL)P001-575-500
RPE-Astral™616496, 546, 566/617 nm100 ug/mL25 tests (125 uL)P001-R616-125
100 tests (500 uL)P001-R616-500
CF®647Plus652/668 nm25 ug/mL25 tests (125 uL)P001-647P-125
100 tests (500 uL)P001-647P-500
CF®660C667/685 nm50 ug/mL25 tests (125 uL)P001-660C-125CF®660C Features
100 tests (500 uL)P001-660C-500
CF®700696/721 nm25 ug/mL25 tests (125 uL)P001-700-125CF®700 Features
100 tests (500 uL)P001-700-500
CF®820822/835 nm20 ug/mL25 tests (125 uL)P001-820-125CF®820 Features
100 tests (500 uL)P001-820-500
APC-Astral™813633, 638/813 nm50 ug/mL25 tests (125 uL)P001-A813-125
100 tests (500 uL)P001-A813-500
R-PE496, 546, 565/576 nm25 ug/mL25 tests (125 uL)P001-RPE-125
100 tests (500 uL)P001-RPE-500
APC651/660 nm50 ug/mL25 tests (125 uL)P001-APC-125
100 tests (500 uL)P001-APC-500
 

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