Monoclonal anti IgA Secretory Component (SC05)

Price:

from

$120.00

Catalog #: BNUB0050

Selection:

Multiple sizes

Category: Primary Antibodies.

>>> Order 5 or more and receive 10% off.

Description
References
More Info
Downloads
Shipping/shelf life

Product Description

This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

Bartek J et. al. Histochemistry 91:235-244 (1989). | Int. J. Cancer, 42, 638-641 (1988). | Histochem J., 22, (1990)

Additional Information

Conjugation	Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP
Size	50 uL, 100 uL, 250 uL, 500 uL
Supplied As	Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA
Antibody type	Primary
Host species	Mouse
Reactivity (target)	IgA Secretory Component (SC05)
Clonality	Monoclonal
Isotype	IgG1, kappa
Clone	SC05
Molecular weight	~80 kDa
Synonyms	ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD
Entrez gene ID	1893
SwissProt	Q16610
Unigene	81071
Immunogen	Secretory Component protein isolated from human colostrum
Species reactivity	Human, Rat
Applications	Flow cytometry, Immunofluorescence, Immunohistology (formalin)
Cellular localization	Cell surface and cytoplasmic
Application notes	Flow Cytometry (0.5-1 ug/million cells/0.1 mL), Immunofluorescence 1-2 ug/mL, Immunohistology formalin-fixed 0.5-1 ug/mL for 30 minutes at RT, Optimal dilution for a specific application should be determined by user, Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
Positive control	Stomach, Lung, or breast tumor

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

Shipment Method: Shipping and handling methods will be assessed and calculated at time of shipment based upon item(s) storage temperature conditions.

Expedited shipment may be requested at time of checkout.

Please note that products with recommended storage at 4°C or -20°C may ship at ambient temperature. This will not affect product performance. When you receive the product, place it under the recommended storage conditions.

More information about product handling and shelf life