Monoclonal anti Kappa Light Chain (Kap 56)

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Catalog #: BNUB0859
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Product Description

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Kiyotaki M et. al. J Immunol. 1987;138(12):4150-8. | Nakamura T et. al. Proc Natl Acad Sci U S A. 1992;89(18):8522-6

Additional Information


Purified with BSA, 0.2 mg/mL, Purified, BSA-free, 1 mg/mL, CF405S, CF405M, CF488A, CF543, CF555, CF568, CF594, CF640R, CF647, CF660R, CF680, CF680R, CF770, Biotin, R-PE, APC, Per-CP, Alkaline Phosphatase, HRP


50 uL, 100 uL, 250 uL, 500 uL

Supplied As

Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide, Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA

Antibody type


Host species


Reactivity (target)

Kappa Light Chain (Kap-56)






IgG1, kappa

Molecular weight

~22.5 kDa


HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM

Entrez gene ID



P01601 & P01834


Human lymphocytes stimulated



Species reactivity



Flow cytometry, Immunohistology (formalin), Western

Cellular localization

Cell surface, cytoplasmic and secreted

Application notes

Flow Cytometry 0.5-2.0 ug/million cells in 0.1 mL, Immunohistology formalin-fixed 0.5-1.0 ug/mL for 30 min at RT, Optimal dilution for a specific application should be determined by user, Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes, Western blotting 0.5-1.0 ug/mL

Positive control

293T, Raji or hPBL cells. Tonsil or Spleen

MSDS (PDF):MSDS Primary antibodies

Protocol (PDF): Protocols for antibody-based detection

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