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Oxazole Yellow Homodimer (YOYO®-1), 1 mM in DMSO

Oxazole yellow homodimer, also known as YOYO®-1, is a green-fluorescent, cell-impermeant nucleic acid stain that can be used to stain dead or fixed cells.

Product Attributes

Cellular localization

Nucleus & cytoplasm

Assay type/options

No-wash staining, Real-time imaging

Cell permeability

Membrane impermeant

Colors

Green

Excitation/Emission

491/509 nm (with DNA)

Note: Due to operating restrictions related to our COVID-19 response, primary antibody conjugates of R-PE, APC, PerCP, HRP, or AP are temporarily unavailable. All other antibody options are still available. We apologize for the inconvenience. Please see our easy-to-use Mix-n-Stain™ Antibody Labeling Kits for labeling antibodies with R-PE, APC, tandem dyes, and enzymes.
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100 uL (1 mM in DMSO)
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Product Description

Oxazole yellow homodimer, also known as YOYO®-1, is a green-fluorescent, cell-impermeant, high-affinity carbocyanine dimeric nucleic acid stain.

  • Dimeric nucleic acid stain
  • Cell-impermeant
  • λExEm (with DNA) = 491/509 nm
  • Supplied at 1 mM in DMSO

The dye is essentially non-fluorescent in the absence of nucleic acids but exhibits strong excitation/emission maxima 491/509 nm when bound to nucleic acids. In addition, the dye is non-cytotoxic and may be used for long-term monitoring of viability in cell cultures.

 

References

  1. J Biomol Struct Dyn, 16(2), 205(1998), DOI: 10.1080/07391102.1998.10508240.
  2. Endocrinology, 143(3), 1058(2002), DOI: 10.1210/endo.143.3.8665
  3. Biopolymers, 36(2), 153(1995), DOI: 10.1002/bip.360360205
  4. Beilstein J Nanotechnology, 8(1), 2296(2017), DOI: 10.3762/bjnano.8.229
  5. Scientific Reports, 10(1), 12504(2020), DOI: 10.1038/s41598-020-68892-5
  6. Organic & Biomol Chem, 17(2), 215(2019), DOI: 10.1039/c8ob02711k
 

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