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TMRE

TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation.

Product Attributes

CAS number

115532-52-0

Cellular localization

Mitochondria

For live or fixed cells

For live/intact cells

Assay type/options

Real-time imaging

Cell permeability

Membrane permeant

Apoptosis/viability marker

Mitochondrial potential

Potential dependence

Mitochondrial potential-dependent

Colors

Red

Excitation/Emission

549/574 nm

Size
Catalog #
price
Qty
25 mg
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Product Description

TMRE (Tetramethylrhodamine ethyl ester, perchlorate) and TMRM (70017) are preferred dyes for quantitative measurements of membrane potentials using the Nernst equation. The dyes do not form aggregates in cell membranes and have minimal interaction with membrane proteins. Thus, the transmembrane distribution of the dyes is directly related to the membrane potential according to the Nernst equation. Biotium also offers TMRE, 2 mM in DMSO (70005) as a ready to use stock solution.

  • λExEm (MeOH) = 549/574 nm
  • Red solid soluble in DMSO, DMF or EtOH
  • Store at 4°C and protect from light
  • C26H27ClN2O7
  • MW: 515
  • [115532-52-0]

 

References

1. Meth Cell Biol 38, 195 (1993).

2. Meth Cell Biol 30, 193 (1989).

3. Biophys J 56, 1053 (1989).

4. Biophys J 53, 785 (1988).

 

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