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Calcium Indicators & Chelators

Biotium offers a wide range of calcium indicator dyes, including Fluo-4 AM Ester, a bright and cell permeable dye that is used for high-throughput screening.

The calcium indicator dyes vary in their calcium dissociation constant (Kd), color and brightness. The AM ester versions are cell permeable, and hydrolyzed by intracellular esterases to release the fluorescent dye. See our complete selection of Calcium & Other Ion Indicators, or download the Ion Indicator Brochure to learn more.

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    Product

    DMNP-EDTA (Caged Calcium), AM Ester

    From: $125 Sizes: 1 mg, 5 mgCatalog #:
    50051-5mg
    , - 50051-1mgView allHide

    The membrane-permeant form of DMNP-EDTA (also known as DM-Nitrophen™), a photolyzable calcium chelator that can be used to release a pulse of calcium when exposed to light.

     
    Product

    4-Bromo A-23187, Free Acid

    From: $205 Sizes: 1 mgCatalog #: 59006

    Similar to A-23187, 4-Bromo A-23187 is used for in situ calibrations of fluorescent Ca2+ indicators to equilibrate intracellular and extracellular calcium concentrations and to allow Mn2+ to enter cells to quench indicator fluorescence.

     
    Product

    5,5′-Dibromo BAPTA, Tetrapotassium Salt

    From: $192 Sizes: 100 mgCatalog #: 50004

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    5,5′-Difluoro BAPTA, AM Ester

    From: $318 Sizes: 25 mgCatalog #: 50005

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    5,5′-Difluoro BAPTA, Tetrapotassium Salt

    From: $259 Sizes: 100 mgCatalog #: 50006

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    5,5′-Dimethyl BAPTA, AM Ester

    From: $250 Sizes: 25 mgCatalog #: 50007

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    5,5′-Dimethyl BAPTA, Tetrapotassium Salt

    From: $121 Sizes: 100 mgCatalog #: 50008

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    A-23187 Free Acid

    From: $67 Sizes: 1 mgCatalog #: 59001

    A-23187, also known as Calcimycin or Calcium Ionophore III, is a calcium ionophore that rapidly equilibrates intracellular and extracellular calcium concentrations. It is commonly used for in situ calibrations of fluorescent calcium indicators.

     
    Product

    BAPTA, AM Ester

    From: $253 Sizes: 20 x 1 mg, 25 mgCatalog #:
    50000
    , - 50000-1View allHide

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    BAPTA, Tetracesium Salt

    From: $374 Sizes: 1 gCatalog #: 50001

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    BAPTA, Tetrapotassium Salt

    From: $253 Sizes: 1 gCatalog #: 50002

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    BAPTA, Tetrasodium Salt

    From: $253 Sizes: 1 gCatalog #: 50003

    BAPTA and its derivatives are calcium chelators that are commonly used to form calcium buffers with well-defined calcium concentrations. By injecting the chelators into cells or by incubating cells with the AM ester form of the chelators, one can control the cytosolic calcium concentration, an important means to study the roles of calcium.

     
    Product

    Calcium Calibration Buffer Kit

    From: $229 Sizes: 1 kitCatalog #: 59100

    This kit provides buffers for generating a range of accurate calcium concentrations for the calibration of fluorescent Ca2+ indicators.

     
    Product

    DMNP-EDTA, Tetrapotassium Salt (Caged Calcium)

    From: $397 Sizes: 5 mgCatalog #: 50050

    DMNP-EDTA (also known as DM-Nitrophen™) is a caged calcium chelator. Upon photolysis, the Kd for Ca2+ increases from 5 nM to 3 mM, resulting in a pulse of free Ca2+.

     
    Product

    DMSO, Anhydrous

    From: $31 Sizes: 10 mLCatalog #: 90082

    Anhydrous DMSO (dimethyl sulfoxide; methyl sulfoxide) is recommended for preparing stock solutions of AM ester dyes, reactive dyes and other related moisture-sensitive products.

     
    Product

    EDC (EDAC)

    From: $98 Sizes: 100 mgCatalog #: 59002

    EDC (or EDAC) (1-(3-Dimethylaminopropyl-3-ethylcarbodiimide, hydrochloride)) has recently been found to be very useful for fixing in situ chelators, including the fluorescent ion indicators for histological studies following physiological experiments. EDC is also a widely used reagent to activate carboxy groups for amine coupling.