CF® dye with TCO (trans-cyclooctene) reacts with tetrazine containing molecules via copper free click chemistry. This copper free bioorthogonal reaction is useful for labeling live cells, or when there are concerns about native protein function loss with copper in cell extracts.
CF® dyes are exceptionally bright and photostable, making them the perfect dyes for fluorescence detection. The following CF® dyes are available with TCO: CF®488A, CF®500, CF®532, CF®555, CF®568, CF®594, CF®640R, CF®647, CF®650, CF®680, and CF®680R.
CF®500 TCO and CF®650 TCO are designed to use for intracellular copper free reaction with tetrazine. CF®488A, CF®532, CF®555, CF®568, CF®594, CF®640R, CF®647, CF®680, and CF®680R are cell-membrane impermeant.
We also offer CF® dye tetrazine and CF® dye methyltetrazine.
CF Dye TCO: Product & SKU Summary