CF® dye with a methyltetrazine group react with cyclooctene (TCO, methylcyclopropene) containing molecules via copper-free click chemistry. This copper-free bioorthogonal reaction is useful for labeling live cells, or when there are concerns about native protein function loss with copper in cell extracts. Membrane-permeant CF® dye methyltetrazine options are also available for intracellular labeling reactions.
Available CF® dye methyltetrazine derivatives: CF®488A, CF®532, CF®555, CF®568, CF®594, CF®640R, CF®647, CF®680, and CF®680R including membrane-permeant CF®500, and CF®650 methyltetrazine.
- Fluorescent labeling of cyclooctene (TCO, methylcyclopropene) groups on target molecules via copper-free bioorthonal chemistry.
- Membrane-impermeant and membrane-permeant forms for surface or intracellular labeling of live cells or cell extracts.
- Bright, photostable and water-soluble CF® dyes are excellent options for fluorescent labeling.
CF® dye methyltetrazines have improved chemical stability compared to CF® dye tetrazines. We also offer CF® dye TCO.
Superior CF® Dyes
Biotium’s next-generation CF® dyes were designed to be highly water-soluble with advantages in brightness and photostability compared to Alexa Fluor®, DyLight®, and other fluorescent dyes. Learn more about CF® Dyes. For more information download the CF® Dye Brochure.
CF Dye Methyltetrazine: Product & SKU Summary